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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TXNL1
All Species:
31.82
Human Site:
S212
Identified Species:
53.85
UniProt:
O43396
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43396
NP_004777.1
289
32251
S212
D
F
E
E
A
E
R
S
E
P
T
Q
A
L
E
Chimpanzee
Pan troglodytes
XP_001137336
285
31851
A209
R
S
M
D
F
E
E
A
E
R
S
E
P
T
Q
Rhesus Macaque
Macaca mulatta
XP_001083710
289
32176
S212
D
F
E
E
A
E
R
S
E
P
T
Q
A
L
E
Dog
Lupus familis
XP_541090
267
30276
Q191
A
E
R
S
E
P
T
Q
A
L
E
L
T
E
D
Cat
Felis silvestris
Mouse
Mus musculus
Q8CDN6
289
32219
S212
D
F
E
E
A
E
R
S
E
P
T
Q
A
L
E
Rat
Rattus norvegicus
Q920J4
289
32231
S212
D
F
E
E
A
E
R
S
E
P
T
Q
A
L
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510259
342
37565
S265
D
F
E
E
A
E
R
S
E
P
T
Q
A
L
E
Chicken
Gallus gallus
XP_424463
289
32335
S212
D
F
E
E
A
E
R
S
E
P
T
Q
A
L
E
Frog
Xenopus laevis
NP_001089222
289
32020
S212
D
F
D
E
A
M
R
S
E
P
T
Q
A
V
E
Zebra Danio
Brachydanio rerio
NP_957432
289
31983
S212
G
F
D
D
A
E
R
S
E
A
T
Q
S
L
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_523938
287
31709
M210
D
F
D
M
A
E
S
M
N
S
V
Q
D
L
S
Honey Bee
Apis mellifera
XP_623128
287
31633
N210
D
F
D
M
A
D
S
N
T
S
I
Q
D
L
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786407
287
31919
R210
L
S
F
D
A
A
E
R
M
E
A
V
Q
E
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SQZ9
176
19652
S100
N
K
E
H
M
C
F
S
N
V
N
D
F
P
P
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.5
99.6
88.9
N.A.
98.6
98.9
N.A.
77.4
91.6
84
80.6
N.A.
49.8
50.1
N.A.
49.8
Protein Similarity:
100
97.5
99.6
89.9
N.A.
99.3
99.6
N.A.
81.2
96.8
93.4
90.6
N.A.
67.8
66.7
N.A.
68.5
P-Site Identity:
100
13.3
100
0
N.A.
100
100
N.A.
100
100
80
60
N.A.
40
33.3
N.A.
6.6
P-Site Similarity:
100
46.6
100
6.6
N.A.
100
100
N.A.
100
100
93.3
86.6
N.A.
46.6
53.3
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
26.9
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
39.4
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
79
8
0
8
8
8
8
0
50
0
0
% A
% Cys:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% C
% Asp:
65
0
29
22
0
8
0
0
0
0
0
8
15
0
15
% D
% Glu:
0
8
50
50
8
65
15
0
65
8
8
8
0
15
50
% E
% Phe:
0
72
8
0
8
0
8
0
0
0
0
0
8
0
0
% F
% Gly:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% I
% Lys:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
8
0
0
0
0
0
0
0
0
8
0
8
0
65
8
% L
% Met:
0
0
8
15
8
8
0
8
8
0
0
0
0
0
0
% M
% Asn:
8
0
0
0
0
0
0
8
15
0
8
0
0
0
0
% N
% Pro:
0
0
0
0
0
8
0
0
0
50
0
0
8
8
8
% P
% Gln:
0
0
0
0
0
0
0
8
0
0
0
72
8
0
8
% Q
% Arg:
8
0
8
0
0
0
58
8
0
8
0
0
0
0
0
% R
% Ser:
0
15
0
8
0
0
15
65
0
15
8
0
8
0
8
% S
% Thr:
0
0
0
0
0
0
8
0
8
0
58
0
8
8
8
% T
% Val:
0
0
0
0
0
0
0
0
0
8
8
8
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _