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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TXNL1 All Species: 23.94
Human Site: S261 Identified Species: 40.51
UniProt: O43396 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43396 NP_004777.1 289 32251 S261 E E E T T R I S Y F T F I G T
Chimpanzee Pan troglodytes XP_001137336 285 31851 T258 N Q G E E E T T R I S Y F T F
Rhesus Macaque Macaca mulatta XP_001083710 289 32176 S261 E E E T T R I S Y F T F I G T
Dog Lupus familis XP_541090 267 30276 F240 T R I S Y F T F I G T P V Q A
Cat Felis silvestris
Mouse Mus musculus Q8CDN6 289 32219 S261 E E E T T R I S Y F T F I G T
Rat Rattus norvegicus Q920J4 289 32231 S261 E E E T T R I S Y F T F I G T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510259 342 37565 S314 E E E T T R V S Y F T F I G T
Chicken Gallus gallus XP_424463 289 32335 T261 D E E T T R I T Y F T F I G T
Frog Xenopus laevis NP_001089222 289 32020 A261 D E E A T R I A Y L T F I G T
Zebra Danio Brachydanio rerio NP_957432 289 31983 N261 D E E T T K I N Y L T F I G T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_523938 287 31709 D259 G G D V T Q I D Y I G F I G S
Honey Bee Apis mellifera XP_623128 287 31633 D259 G N E V T R I D H L A I F G S
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_786407 287 31919 Q259 D E E T T T I Q Y I S F I G T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SQZ9 176 19652 V149 A N Q S G S E V T K V Q K I A
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.5 99.6 88.9 N.A. 98.6 98.9 N.A. 77.4 91.6 84 80.6 N.A. 49.8 50.1 N.A. 49.8
Protein Similarity: 100 97.5 99.6 89.9 N.A. 99.3 99.6 N.A. 81.2 96.8 93.4 90.6 N.A. 67.8 66.7 N.A. 68.5
P-Site Identity: 100 0 100 6.6 N.A. 100 100 N.A. 93.3 86.6 73.3 73.3 N.A. 40 33.3 N.A. 66.6
P-Site Similarity: 100 26.6 100 20 N.A. 100 100 N.A. 100 100 86.6 93.3 N.A. 60 46.6 N.A. 80
Percent
Protein Identity: N.A. N.A. N.A. 26.9 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 39.4 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 0 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 8 0 0 0 8 0 0 8 0 0 0 15 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 29 0 8 0 0 0 0 15 0 0 0 0 0 0 0 % D
% Glu: 36 65 72 8 8 8 8 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 8 0 8 0 43 0 72 15 0 8 % F
% Gly: 15 8 8 0 8 0 0 0 0 8 8 0 0 79 0 % G
% His: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % H
% Ile: 0 0 8 0 0 0 72 0 8 22 0 8 72 8 0 % I
% Lys: 0 0 0 0 0 8 0 0 0 8 0 0 8 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 22 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 8 15 0 0 0 0 0 8 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % P
% Gln: 0 8 8 0 0 8 0 8 0 0 0 8 0 8 0 % Q
% Arg: 0 8 0 0 0 58 0 0 8 0 0 0 0 0 0 % R
% Ser: 0 0 0 15 0 8 0 36 0 0 15 0 0 0 15 % S
% Thr: 8 0 0 58 79 8 15 15 8 0 65 0 0 8 65 % T
% Val: 0 0 0 15 0 0 8 8 0 0 8 0 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 8 0 0 0 72 0 0 8 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _