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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TXNL1
All Species:
23.94
Human Site:
S261
Identified Species:
40.51
UniProt:
O43396
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43396
NP_004777.1
289
32251
S261
E
E
E
T
T
R
I
S
Y
F
T
F
I
G
T
Chimpanzee
Pan troglodytes
XP_001137336
285
31851
T258
N
Q
G
E
E
E
T
T
R
I
S
Y
F
T
F
Rhesus Macaque
Macaca mulatta
XP_001083710
289
32176
S261
E
E
E
T
T
R
I
S
Y
F
T
F
I
G
T
Dog
Lupus familis
XP_541090
267
30276
F240
T
R
I
S
Y
F
T
F
I
G
T
P
V
Q
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8CDN6
289
32219
S261
E
E
E
T
T
R
I
S
Y
F
T
F
I
G
T
Rat
Rattus norvegicus
Q920J4
289
32231
S261
E
E
E
T
T
R
I
S
Y
F
T
F
I
G
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510259
342
37565
S314
E
E
E
T
T
R
V
S
Y
F
T
F
I
G
T
Chicken
Gallus gallus
XP_424463
289
32335
T261
D
E
E
T
T
R
I
T
Y
F
T
F
I
G
T
Frog
Xenopus laevis
NP_001089222
289
32020
A261
D
E
E
A
T
R
I
A
Y
L
T
F
I
G
T
Zebra Danio
Brachydanio rerio
NP_957432
289
31983
N261
D
E
E
T
T
K
I
N
Y
L
T
F
I
G
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_523938
287
31709
D259
G
G
D
V
T
Q
I
D
Y
I
G
F
I
G
S
Honey Bee
Apis mellifera
XP_623128
287
31633
D259
G
N
E
V
T
R
I
D
H
L
A
I
F
G
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786407
287
31919
Q259
D
E
E
T
T
T
I
Q
Y
I
S
F
I
G
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SQZ9
176
19652
V149
A
N
Q
S
G
S
E
V
T
K
V
Q
K
I
A
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.5
99.6
88.9
N.A.
98.6
98.9
N.A.
77.4
91.6
84
80.6
N.A.
49.8
50.1
N.A.
49.8
Protein Similarity:
100
97.5
99.6
89.9
N.A.
99.3
99.6
N.A.
81.2
96.8
93.4
90.6
N.A.
67.8
66.7
N.A.
68.5
P-Site Identity:
100
0
100
6.6
N.A.
100
100
N.A.
93.3
86.6
73.3
73.3
N.A.
40
33.3
N.A.
66.6
P-Site Similarity:
100
26.6
100
20
N.A.
100
100
N.A.
100
100
86.6
93.3
N.A.
60
46.6
N.A.
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
26.9
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
39.4
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
8
0
0
0
8
0
0
8
0
0
0
15
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
29
0
8
0
0
0
0
15
0
0
0
0
0
0
0
% D
% Glu:
36
65
72
8
8
8
8
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
8
0
8
0
43
0
72
15
0
8
% F
% Gly:
15
8
8
0
8
0
0
0
0
8
8
0
0
79
0
% G
% His:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% H
% Ile:
0
0
8
0
0
0
72
0
8
22
0
8
72
8
0
% I
% Lys:
0
0
0
0
0
8
0
0
0
8
0
0
8
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
22
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
15
0
0
0
0
0
8
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% P
% Gln:
0
8
8
0
0
8
0
8
0
0
0
8
0
8
0
% Q
% Arg:
0
8
0
0
0
58
0
0
8
0
0
0
0
0
0
% R
% Ser:
0
0
0
15
0
8
0
36
0
0
15
0
0
0
15
% S
% Thr:
8
0
0
58
79
8
15
15
8
0
65
0
0
8
65
% T
% Val:
0
0
0
15
0
0
8
8
0
0
8
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
0
0
72
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _