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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TXNL1 All Species: 25.45
Human Site: S46 Identified Species: 43.08
UniProt: O43396 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43396 NP_004777.1 289 32251 S46 R I A P A F S S M S N K Y P Q
Chimpanzee Pan troglodytes XP_001137336 285 31851 S46 R I A P A F S S M S N K Y P Q
Rhesus Macaque Macaca mulatta XP_001083710 289 32176 S46 R I A P A F S S M S N K Y P Q
Dog Lupus familis XP_541090 267 30276 V36 A V F L E V D V H Q C Q G T A
Cat Felis silvestris
Mouse Mus musculus Q8CDN6 289 32219 S46 R I A P A F S S M S N K Y P Q
Rat Rattus norvegicus Q920J4 289 32231 S46 R I A P A F S S M S N K Y P Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510259 342 37565 A99 R I A P A F N A L S N K Y P Q
Chicken Gallus gallus XP_424463 289 32335 A46 R I A P A F N A L S N K Y P Q
Frog Xenopus laevis NP_001089222 289 32020 S46 R I S P A F T S L S N K Y P H
Zebra Danio Brachydanio rerio NP_957432 289 31983 M46 R I A P A F N M L S N K Y P Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_523938 287 31709 T45 R I A P I F E T F P T K Y P K
Honey Bee Apis mellifera XP_623128 287 31633 Q46 R I A P I F E Q L S L K Y P N
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_786407 287 31919 Q46 T I A P V F A Q L A T A H P N
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SQZ9 176 19652
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.5 99.6 88.9 N.A. 98.6 98.9 N.A. 77.4 91.6 84 80.6 N.A. 49.8 50.1 N.A. 49.8
Protein Similarity: 100 97.5 99.6 89.9 N.A. 99.3 99.6 N.A. 81.2 96.8 93.4 90.6 N.A. 67.8 66.7 N.A. 68.5
P-Site Identity: 100 100 100 0 N.A. 100 100 N.A. 80 80 73.3 80 N.A. 53.3 60 N.A. 33.3
P-Site Similarity: 100 100 100 13.3 N.A. 100 100 N.A. 100 100 93.3 93.3 N.A. 66.6 66.6 N.A. 60
Percent
Protein Identity: N.A. N.A. N.A. 26.9 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 39.4 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 0 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 0 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 79 0 65 0 8 15 0 8 0 8 0 0 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 8 0 15 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 8 0 0 86 0 0 8 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % G
% His: 0 0 0 0 0 0 0 0 8 0 0 0 8 0 8 % H
% Ile: 0 86 0 0 15 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 79 0 0 8 % K
% Leu: 0 0 0 8 0 0 0 0 43 0 8 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 8 36 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 22 0 0 0 65 0 0 0 15 % N
% Pro: 0 0 0 86 0 0 0 0 0 8 0 0 0 86 0 % P
% Gln: 0 0 0 0 0 0 0 15 0 8 0 8 0 0 58 % Q
% Arg: 79 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 8 0 0 0 36 43 0 72 0 0 0 0 0 % S
% Thr: 8 0 0 0 0 0 8 8 0 0 15 0 0 8 0 % T
% Val: 0 8 0 0 8 8 0 8 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 79 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _