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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TXNL1 All Species: 30.91
Human Site: T155 Identified Species: 52.31
UniProt: O43396 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43396 NP_004777.1 289 32251 T155 N C L R K D T T F L E S D C D
Chimpanzee Pan troglodytes XP_001137336 285 31851 K152 G F D N C L R K D T T F L E S
Rhesus Macaque Macaca mulatta XP_001083710 289 32176 T155 N C L R K D T T F L E S D C D
Dog Lupus familis XP_541090 267 30276 S134 K D M T F L E S D C D E Q L L
Cat Felis silvestris
Mouse Mus musculus Q8CDN6 289 32219 S155 N C L R K D M S F L E S D C D
Rat Rattus norvegicus Q920J4 289 32231 S155 N C L R K D L S F L E S D C D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510259 342 37565 S208 N C L R K D P S F L E S D C D
Chicken Gallus gallus XP_424463 289 32335 T155 N C L R K D S T Y L E S D C D
Frog Xenopus laevis NP_001089222 289 32020 T155 N C L R K D P T Y L E S D C D
Zebra Danio Brachydanio rerio NP_957432 289 31983 T155 S C L I K D A T Y L E S D C D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_523938 287 31709 G153 K H A L A S A G G Y L Q S D C
Honey Bee Apis mellifera XP_623128 287 31633 D153 L Q C L N T D D G Y L E S E C
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_786407 287 31919 G153 L E A C L K K G D S Y L E S D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SQZ9 176 19652 G43 L P N A L K Q G Y R E D E G L
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.5 99.6 88.9 N.A. 98.6 98.9 N.A. 77.4 91.6 84 80.6 N.A. 49.8 50.1 N.A. 49.8
Protein Similarity: 100 97.5 99.6 89.9 N.A. 99.3 99.6 N.A. 81.2 96.8 93.4 90.6 N.A. 67.8 66.7 N.A. 68.5
P-Site Identity: 100 0 100 0 N.A. 86.6 86.6 N.A. 86.6 86.6 86.6 73.3 N.A. 0 0 N.A. 6.6
P-Site Similarity: 100 0 100 20 N.A. 93.3 93.3 N.A. 93.3 100 93.3 86.6 N.A. 0 0 N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. 26.9 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 39.4 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 20 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 15 8 8 0 15 0 0 0 0 0 0 0 0 % A
% Cys: 0 58 8 8 8 0 0 0 0 8 0 0 0 58 15 % C
% Asp: 0 8 8 0 0 58 8 8 22 0 8 8 58 8 65 % D
% Glu: 0 8 0 0 0 0 8 0 0 0 65 15 15 15 0 % E
% Phe: 0 8 0 0 8 0 0 0 36 0 0 8 0 0 0 % F
% Gly: 8 0 0 0 0 0 0 22 15 0 0 0 0 8 0 % G
% His: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 15 0 0 0 58 15 8 8 0 0 0 0 0 0 0 % K
% Leu: 22 0 58 15 15 15 8 0 0 58 15 8 8 8 15 % L
% Met: 0 0 8 0 0 0 8 0 0 0 0 0 0 0 0 % M
% Asn: 50 0 8 8 8 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 8 0 0 0 0 15 0 0 0 0 0 0 0 0 % P
% Gln: 0 8 0 0 0 0 8 0 0 0 0 8 8 0 0 % Q
% Arg: 0 0 0 50 0 0 8 0 0 8 0 0 0 0 0 % R
% Ser: 8 0 0 0 0 8 8 29 0 8 0 58 15 8 8 % S
% Thr: 0 0 0 8 0 8 15 36 0 8 8 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 29 15 8 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _