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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TXNL1
All Species:
37.88
Human Site:
Y123
Identified Species:
64.1
UniProt:
O43396
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43396
NP_004777.1
289
32251
Y123
D
T
D
I
P
K
G
Y
M
D
L
M
P
F
I
Chimpanzee
Pan troglodytes
XP_001137336
285
31851
Y123
D
T
D
I
P
K
G
Y
M
D
L
M
P
F
I
Rhesus Macaque
Macaca mulatta
XP_001083710
289
32176
Y123
D
T
D
I
P
K
G
Y
M
D
L
M
P
F
I
Dog
Lupus familis
XP_541090
267
30276
I105
Y
M
D
L
M
P
F
I
N
K
A
G
C
E
C
Cat
Felis silvestris
Mouse
Mus musculus
Q8CDN6
289
32219
Y123
D
A
D
I
P
K
G
Y
M
D
L
M
P
F
I
Rat
Rattus norvegicus
Q920J4
289
32231
Y123
D
T
D
I
P
K
G
Y
M
D
L
M
P
F
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510259
342
37565
Y176
D
T
D
I
P
K
G
Y
M
D
L
M
P
F
I
Chicken
Gallus gallus
XP_424463
289
32335
Y123
D
T
D
I
P
K
G
Y
M
D
L
M
P
F
I
Frog
Xenopus laevis
NP_001089222
289
32020
Y123
D
A
D
I
P
R
G
Y
M
D
L
L
P
F
V
Zebra Danio
Brachydanio rerio
NP_957432
289
31983
Y123
D
S
D
I
P
K
G
Y
M
D
L
M
P
F
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_523938
287
31709
L122
G
E
D
Y
G
Q
G
L
M
E
L
N
T
F
I
Honey Bee
Apis mellifera
XP_623128
287
31633
H122
S
E
S
P
V
S
G
H
M
D
L
A
T
F
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786407
287
31919
Y123
E
G
S
G
V
P
G
Y
I
E
L
N
G
M
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SQZ9
176
19652
V14
S
Q
I
P
K
G
Q
V
D
L
L
D
F
I
D
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.5
99.6
88.9
N.A.
98.6
98.9
N.A.
77.4
91.6
84
80.6
N.A.
49.8
50.1
N.A.
49.8
Protein Similarity:
100
97.5
99.6
89.9
N.A.
99.3
99.6
N.A.
81.2
96.8
93.4
90.6
N.A.
67.8
66.7
N.A.
68.5
P-Site Identity:
100
100
100
6.6
N.A.
93.3
100
N.A.
100
100
73.3
86.6
N.A.
40
40
N.A.
26.6
P-Site Similarity:
100
100
100
13.3
N.A.
93.3
100
N.A.
100
100
93.3
100
N.A.
53.3
46.6
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
26.9
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
39.4
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
15
0
0
0
0
0
0
0
0
8
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
8
% C
% Asp:
65
0
79
0
0
0
0
0
8
72
0
8
0
0
8
% D
% Glu:
8
15
0
0
0
0
0
0
0
15
0
0
0
8
0
% E
% Phe:
0
0
0
0
0
0
8
0
0
0
0
0
8
79
0
% F
% Gly:
8
8
0
8
8
8
86
0
0
0
0
8
8
0
0
% G
% His:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
65
0
0
0
8
8
0
0
0
0
8
72
% I
% Lys:
0
0
0
0
8
58
0
0
0
8
0
0
0
0
0
% K
% Leu:
0
0
0
8
0
0
0
8
0
8
93
8
0
0
0
% L
% Met:
0
8
0
0
8
0
0
0
79
0
0
58
0
8
0
% M
% Asn:
0
0
0
0
0
0
0
0
8
0
0
15
0
0
0
% N
% Pro:
0
0
0
15
65
15
0
0
0
0
0
0
65
0
0
% P
% Gln:
0
8
0
0
0
8
8
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% R
% Ser:
15
8
15
0
0
8
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
43
0
0
0
0
0
0
0
0
0
0
15
0
0
% T
% Val:
0
0
0
0
15
0
0
8
0
0
0
0
0
0
15
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
8
0
0
0
72
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _