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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TXNL1
All Species:
26.67
Human Site:
Y178
Identified Species:
45.13
UniProt:
O43396
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43396
NP_004777.1
289
32251
Y178
F
N
Q
P
V
K
L
Y
S
M
K
F
Q
G
P
Chimpanzee
Pan troglodytes
XP_001137336
285
31851
V175
T
V
A
F
N
Q
P
V
K
L
Y
S
M
K
F
Rhesus Macaque
Macaca mulatta
XP_001083710
289
32176
Y178
F
N
Q
P
V
K
L
Y
S
M
K
F
Q
G
P
Dog
Lupus familis
XP_541090
267
30276
F157
V
K
L
Y
S
M
K
F
Q
G
P
D
N
G
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q8CDN6
289
32219
Y178
F
N
Q
P
V
K
L
Y
S
M
K
F
Q
G
P
Rat
Rattus norvegicus
Q920J4
289
32231
Y178
F
N
Q
P
V
K
L
Y
S
M
K
F
Q
G
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510259
342
37565
Y231
F
N
Q
P
V
K
L
Y
S
M
K
F
Q
G
P
Chicken
Gallus gallus
XP_424463
289
32335
Y178
F
S
Q
P
V
K
L
Y
S
M
K
L
Q
G
P
Frog
Xenopus laevis
NP_001089222
289
32020
Y178
F
N
Q
P
V
K
L
Y
S
M
K
L
Q
G
P
Zebra Danio
Brachydanio rerio
NP_957432
289
31983
F178
F
N
Q
P
V
K
L
F
S
M
K
L
L
S
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_523938
287
31709
I176
T
F
N
Q
A
V
K
I
H
S
L
K
F
K
A
Honey Bee
Apis mellifera
XP_623128
287
31633
V176
A
F
S
Q
A
V
K
V
H
S
L
K
I
K
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786407
287
31919
K176
M
S
F
Q
Q
N
M
K
L
H
S
L
K
V
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SQZ9
176
19652
F66
Q
L
L
I
Y
I
P
F
N
Q
V
I
K
L
H
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.5
99.6
88.9
N.A.
98.6
98.9
N.A.
77.4
91.6
84
80.6
N.A.
49.8
50.1
N.A.
49.8
Protein Similarity:
100
97.5
99.6
89.9
N.A.
99.3
99.6
N.A.
81.2
96.8
93.4
90.6
N.A.
67.8
66.7
N.A.
68.5
P-Site Identity:
100
0
100
6.6
N.A.
100
100
N.A.
100
86.6
93.3
66.6
N.A.
0
0
N.A.
0
P-Site Similarity:
100
13.3
100
13.3
N.A.
100
100
N.A.
100
93.3
93.3
73.3
N.A.
0
0
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
26.9
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
39.4
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
0
15
0
0
0
0
0
0
0
0
0
22
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
58
15
8
8
0
0
0
22
0
0
0
36
8
0
8
% F
% Gly:
0
0
0
0
0
0
0
0
0
8
0
0
0
58
0
% G
% His:
0
0
0
0
0
0
0
0
15
8
0
0
0
0
8
% H
% Ile:
0
0
0
8
0
8
0
8
0
0
0
8
8
0
0
% I
% Lys:
0
8
0
0
0
58
22
8
8
0
58
15
15
22
0
% K
% Leu:
0
8
15
0
0
0
58
0
8
8
15
29
8
8
8
% L
% Met:
8
0
0
0
0
8
8
0
0
58
0
0
8
0
0
% M
% Asn:
0
50
8
0
8
8
0
0
8
0
0
0
8
0
0
% N
% Pro:
0
0
0
58
0
0
15
0
0
0
8
0
0
0
50
% P
% Gln:
8
0
58
22
8
8
0
0
8
8
0
0
50
0
8
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
15
8
0
8
0
0
0
58
15
8
8
0
8
0
% S
% Thr:
15
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
8
8
0
0
58
15
0
15
0
0
8
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
8
0
0
50
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _