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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: COCH All Species: 30.91
Human Site: S115 Identified Species: 97.14
UniProt: O43405 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43405 NP_001128530.1 550 59483 S115 G I Q S Q M L S R W S A S F T
Chimpanzee Pan troglodytes XP_001171019 569 61641 S115 G I Q S Q M L S R W S A S F T
Rhesus Macaque Macaca mulatta XP_001114785 550 59495 S115 G I Q S Q M L S R W S A S F T
Dog Lupus familis XP_547762 847 90505 S412 G I Q S Q T L S R W S A S F T
Cat Felis silvestris
Mouse Mus musculus Q62507 552 59931 S117 G I Q S Q M L S R W S A S F A
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512838 692 75017 T257 G I Q S Q M L T R W S S S F T
Chicken Gallus gallus O42163 547 59408 S111 G I Q S Q V L S R W A S S F S
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001003823 553 60333 S114 G V Q S Q S L S Q W S A S F T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 96.4 99.6 62.6 N.A. 94 N.A. N.A. 66.3 78.3 N.A. 59.1 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 96.6 99.8 63.7 N.A. 96.5 N.A. N.A. 74.1 89.4 N.A. 75.2 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 93.3 N.A. 93.3 N.A. N.A. 86.6 73.3 N.A. 80 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 93.3 N.A. 93.3 N.A. N.A. 100 100 N.A. 93.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 13 75 0 0 13 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 % F
% Gly: 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 88 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 63 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 100 0 100 0 0 0 13 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 88 0 0 0 0 0 0 % R
% Ser: 0 0 0 100 0 13 0 88 0 0 88 25 100 0 13 % S
% Thr: 0 0 0 0 0 13 0 13 0 0 0 0 0 0 75 % T
% Val: 0 13 0 0 0 13 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _