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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ERI3 All Species: 18.79
Human Site: S22 Identified Species: 41.33
UniProt: O43414 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43414 NP_076971.1 337 37238 S22 P W E G G L V S W P P A P P L
Chimpanzee Pan troglodytes XP_513102 490 52241 S147 P W E G G L V S W P P A P P L
Rhesus Macaque Macaca mulatta XP_001093178 462 49348 S119 P W E G G L V S W P P A P P L
Dog Lupus familis XP_850849 335 37005 S22 P W E G G L V S W P P A P P L
Cat Felis silvestris
Mouse Mus musculus Q8C460 337 37171 S22 P W E G G L V S W P P A P P L
Rat Rattus norvegicus Q5FVR4 345 39562 R20 A A Q Q K T P R P E C E E S R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513729 85 9703
Chicken Gallus gallus XP_422418 265 29706
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_001120094 204 23840
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001175832 268 30962
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8W566 337 38652 T21 R I S P F R D T R F S Y P A T
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 68.7 72.9 98.2 N.A. 97.9 29.2 N.A. 24.6 70.9 N.A. N.A. N.A. N.A. 24.6 N.A. 40.9
Protein Similarity: 100 68.7 72.9 98.5 N.A. 98.5 44 N.A. 24.9 74.1 N.A. N.A. N.A. N.A. 35.9 N.A. 55.7
P-Site Identity: 100 100 100 100 N.A. 100 0 N.A. 0 0 N.A. N.A. N.A. N.A. 0 N.A. 0
P-Site Similarity: 100 100 100 100 N.A. 100 6.6 N.A. 0 0 N.A. N.A. N.A. N.A. 0 N.A. 0
Percent
Protein Identity: N.A. N.A. N.A. 26.4 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 46.5 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 10 0 0 0 0 0 0 0 0 0 46 0 10 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 46 0 0 0 0 0 0 10 0 10 10 0 0 % E
% Phe: 0 0 0 0 10 0 0 0 0 10 0 0 0 0 0 % F
% Gly: 0 0 0 46 46 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 46 0 0 0 0 0 0 0 0 46 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 46 0 0 10 0 0 10 0 10 46 46 0 55 46 0 % P
% Gln: 0 0 10 10 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 10 0 0 0 0 10 0 10 10 0 0 0 0 0 10 % R
% Ser: 0 0 10 0 0 0 0 46 0 0 10 0 0 10 0 % S
% Thr: 0 0 0 0 0 10 0 10 0 0 0 0 0 0 10 % T
% Val: 0 0 0 0 0 0 46 0 0 0 0 0 0 0 0 % V
% Trp: 0 46 0 0 0 0 0 0 46 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _