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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ERI3
All Species:
19.7
Human Site:
S92
Identified Species:
43.33
UniProt:
O43414
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43414
NP_076971.1
337
37238
S92
T
G
A
A
R
F
S
S
Y
L
L
S
R
A
R
Chimpanzee
Pan troglodytes
XP_513102
490
52241
S217
T
G
A
A
R
F
S
S
Y
L
L
S
R
A
R
Rhesus Macaque
Macaca mulatta
XP_001093178
462
49348
S189
T
G
A
A
R
F
S
S
Y
L
L
S
R
A
R
Dog
Lupus familis
XP_850849
335
37005
S90
T
G
A
A
R
F
S
S
Y
L
L
S
R
A
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8C460
337
37171
S92
T
G
A
A
R
F
S
S
Y
L
L
S
R
A
R
Rat
Rattus norvegicus
Q5FVR4
345
39562
K88
R
A
K
L
S
E
F
K
L
E
T
R
G
V
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513729
85
9703
Chicken
Gallus gallus
XP_422418
265
29706
G42
L
P
T
A
L
L
K
G
Y
S
S
V
I
S
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001120094
204
23840
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001175832
268
30962
S46
T
P
R
L
L
A
R
S
F
P
P
S
S
K
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8W566
337
38652
C91
L
Y
Y
T
H
G
K
C
T
K
M
D
D
P
A
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
68.7
72.9
98.2
N.A.
97.9
29.2
N.A.
24.6
70.9
N.A.
N.A.
N.A.
N.A.
24.6
N.A.
40.9
Protein Similarity:
100
68.7
72.9
98.5
N.A.
98.5
44
N.A.
24.9
74.1
N.A.
N.A.
N.A.
N.A.
35.9
N.A.
55.7
P-Site Identity:
100
100
100
100
N.A.
100
0
N.A.
0
20
N.A.
N.A.
N.A.
N.A.
0
N.A.
20
P-Site Similarity:
100
100
100
100
N.A.
100
6.6
N.A.
0
26.6
N.A.
N.A.
N.A.
N.A.
0
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
26.4
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
46.5
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
46
55
0
10
0
0
0
0
0
0
0
46
10
% A
% Cys:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
10
10
0
0
% D
% Glu:
0
0
0
0
0
10
0
0
0
10
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
46
10
0
10
0
0
0
0
0
0
% F
% Gly:
0
46
0
0
0
10
0
10
0
0
0
0
10
0
0
% G
% His:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% I
% Lys:
0
0
10
0
0
0
19
10
0
10
0
0
0
10
10
% K
% Leu:
19
0
0
19
19
10
0
0
10
46
46
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
19
0
0
0
0
0
0
0
10
10
0
0
10
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% Q
% Arg:
10
0
10
0
46
0
10
0
0
0
0
10
46
0
55
% R
% Ser:
0
0
0
0
10
0
46
55
0
10
10
55
10
10
0
% S
% Thr:
55
0
10
10
0
0
0
0
10
0
10
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
10
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
10
0
0
0
0
0
55
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _