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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ERI3
All Species:
18.18
Human Site:
Y145
Identified Species:
40
UniProt:
O43414
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43414
NP_076971.1
337
37238
Y145
F
P
P
Q
R
Y
H
Y
F
L
V
L
D
F
E
Chimpanzee
Pan troglodytes
XP_513102
490
52241
Y270
F
P
P
Q
R
Y
H
Y
F
L
V
L
D
F
E
Rhesus Macaque
Macaca mulatta
XP_001093178
462
49348
Y242
F
P
P
Q
R
Y
H
Y
F
L
V
L
D
F
E
Dog
Lupus familis
XP_850849
335
37005
Y143
F
P
P
Q
R
Y
H
Y
F
L
V
L
D
F
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8C460
337
37171
Y145
F
P
P
Q
R
Y
H
Y
F
L
V
L
D
F
E
Rat
Rattus norvegicus
Q5FVR4
345
39562
A141
T
C
E
E
G
N
P
A
E
F
L
H
E
I
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513729
85
9703
Chicken
Gallus gallus
XP_422418
265
29706
E95
I
H
P
Q
E
I
I
E
F
P
I
L
K
L
N
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001120094
204
23840
C34
L
L
V
L
D
F
E
C
T
C
K
K
Y
E
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001175832
268
30962
V99
E
R
I
E
P
Q
E
V
I
E
F
P
V
L
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8W566
337
38652
P144
K
V
E
I
L
E
F
P
I
L
I
V
D
A
K
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
68.7
72.9
98.2
N.A.
97.9
29.2
N.A.
24.6
70.9
N.A.
N.A.
N.A.
N.A.
24.6
N.A.
40.9
Protein Similarity:
100
68.7
72.9
98.5
N.A.
98.5
44
N.A.
24.9
74.1
N.A.
N.A.
N.A.
N.A.
35.9
N.A.
55.7
P-Site Identity:
100
100
100
100
N.A.
100
0
N.A.
0
26.6
N.A.
N.A.
N.A.
N.A.
0
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
100
20
N.A.
0
33.3
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
26.4
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
46.5
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
10
0
0
0
0
0
10
0
% A
% Cys:
0
10
0
0
0
0
0
10
0
10
0
0
0
0
0
% C
% Asp:
0
0
0
0
10
0
0
0
0
0
0
0
55
0
0
% D
% Glu:
10
0
19
19
10
10
19
10
10
10
0
0
10
10
46
% E
% Phe:
46
0
0
0
0
10
10
0
55
10
10
0
0
46
0
% F
% Gly:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
10
0
0
0
0
46
0
0
0
0
10
0
0
0
% H
% Ile:
10
0
10
10
0
10
10
0
19
0
19
0
0
10
10
% I
% Lys:
10
0
0
0
0
0
0
0
0
0
10
10
10
0
28
% K
% Leu:
10
10
0
10
10
0
0
0
0
55
10
55
0
19
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
10
% N
% Pro:
0
46
55
0
10
0
10
10
0
10
0
10
0
0
0
% P
% Gln:
0
0
0
55
0
10
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
10
0
0
46
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
10
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% T
% Val:
0
10
10
0
0
0
0
10
0
0
46
10
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
46
0
46
0
0
0
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _