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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PRKRIR All Species: 18.18
Human Site: S389 Identified Species: 66.67
UniProt: O43422 Number Species: 6
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43422 NP_004696.2 761 87704 S389 G T I E E V C S F F H R S P Q
Chimpanzee Pan troglodytes XP_001162982 733 84446 S361 G T I E E V C S F F H R S P Q
Rhesus Macaque Macaca mulatta XP_001086430 761 87493 S389 G T I E E V C S F F H R S P Q
Dog Lupus familis XP_542300 762 87726 S390 G T I E E V C S F F H R S P Q
Cat Felis silvestris
Mouse Mus musculus Q9CUX1 758 87003 S385 G T I E E V C S F F H R S P Q
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520443 764 85122 A376 G T M E E V C A F F R Q A P P
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001002680 746 85927 A384 S V L K K S N A F F R A S P L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 96.1 98.9 97.2 N.A. 95 N.A. N.A. 73.8 N.A. N.A. 56.7 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 96.1 99.2 98.8 N.A. 97.5 N.A. N.A. 85.7 N.A. N.A. 75.4 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 100 N.A. N.A. 60 N.A. N.A. 26.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 N.A. N.A. 86.6 N.A. N.A. 53.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 29 0 0 0 15 15 0 0 % A
% Cys: 0 0 0 0 0 0 86 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 86 86 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 100 100 0 0 0 0 0 % F
% Gly: 86 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 72 0 0 0 0 % H
% Ile: 0 0 72 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 15 15 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 15 0 0 0 0 0 0 0 0 0 0 0 15 % L
% Met: 0 0 15 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 15 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 100 15 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 15 0 0 72 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 29 72 0 0 0 % R
% Ser: 15 0 0 0 0 15 0 72 0 0 0 0 86 0 0 % S
% Thr: 0 86 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 15 0 0 0 86 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _