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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GRID2 All Species: 23.94
Human Site: S136 Identified Species: 47.88
UniProt: O43424 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43424 NP_001501.2 1007 113356 S136 S G C G L T R S N R N D D Y T
Chimpanzee Pan troglodytes Q5IS46 956 107246 F129 A P E E F V K F Q F Q R F T T
Rhesus Macaque Macaca mulatta XP_001102156 1007 113295 S136 S G C G L T R S N R N D D Y T
Dog Lupus familis XP_544985 967 108744 T121 D V I L R V V T E Y A W Q K F
Cat Felis silvestris
Mouse Mus musculus Q61625 1007 113063 S136 S G C G L T R S N R N D D Y T
Rat Rattus norvegicus Q63226 1007 113240 S136 S G C G L T R S N R N D D Y T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509188 1007 112958 S135 S G C G L T R S N R N D D Y T
Chicken Gallus gallus XP_420483 1014 113785 S143 S S C G L T R S N R N D D Y T
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q68Y21 1009 113606 R136 S S C P P T T R A Q P D D Y T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q03445 991 111650 A148 S S G L L D F A I S M R P D Y
Honey Bee Apis mellifera XP_394265 861 97699 K45 A F R Y A V E K I N A N R D I
Nematode Worm Caenorhab. elegans Q10914 977 111770 S128 I D W E P S K S E N I G K T T
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 26.7 99.6 92.2 N.A. 97.6 97.7 N.A. 92.6 93.3 N.A. 81.8 N.A. 21 27 22.8 N.A.
Protein Similarity: 100 46 99.9 93.6 N.A. 99 99.1 N.A. 96.6 97.3 N.A. 90.4 N.A. 41.6 46.5 44.1 N.A.
P-Site Identity: 100 6.6 100 0 N.A. 100 100 N.A. 100 93.3 N.A. 46.6 N.A. 13.3 0 13.3 N.A.
P-Site Similarity: 100 20 100 6.6 N.A. 100 100 N.A. 100 93.3 N.A. 53.3 N.A. 20 13.3 26.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 17 0 0 0 9 0 0 9 9 0 17 0 0 0 0 % A
% Cys: 0 0 59 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 9 9 0 0 0 9 0 0 0 0 0 59 59 17 0 % D
% Glu: 0 0 9 17 0 0 9 0 17 0 0 0 0 0 0 % E
% Phe: 0 9 0 0 9 0 9 9 0 9 0 0 9 0 9 % F
% Gly: 0 42 9 50 0 0 0 0 0 0 0 9 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 9 0 9 0 0 0 0 0 17 0 9 0 0 0 9 % I
% Lys: 0 0 0 0 0 0 17 9 0 0 0 0 9 9 0 % K
% Leu: 0 0 0 17 59 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 50 17 50 9 0 0 0 % N
% Pro: 0 9 0 9 17 0 0 0 0 0 9 0 9 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 9 9 9 0 9 0 0 % Q
% Arg: 0 0 9 0 9 0 50 9 0 50 0 17 9 0 0 % R
% Ser: 67 25 0 0 0 9 0 59 0 9 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 59 9 9 0 0 0 0 0 17 75 % T
% Val: 0 9 0 0 0 25 9 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 9 0 0 0 0 0 0 0 0 9 0 0 0 % W
% Tyr: 0 0 0 9 0 0 0 0 0 9 0 0 0 59 9 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _