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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GRID2 All Species: 15.45
Human Site: T46 Identified Species: 30.91
UniProt: O43424 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43424 NP_001501.2 1007 113356 T46 K D D E V F R T A V G D L N Q
Chimpanzee Pan troglodytes Q5IS46 956 107246 L47 G E R L S I T L A K N R I N R
Rhesus Macaque Macaca mulatta XP_001102156 1007 113295 T46 K D D E V F R T A V G D L N Q
Dog Lupus familis XP_544985 967 108744 C43 M E H I L E A C E L M N Q G I
Cat Felis silvestris
Mouse Mus musculus Q61625 1007 113063 T46 K D D E V F R T A V G D L N Q
Rat Rattus norvegicus Q63226 1007 113240 T46 K D D E V F R T A V G D L N Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509188 1007 112958 V45 K D D E V F R V A V A D L N Q
Chicken Gallus gallus XP_420483 1014 113785 M53 K D E E V F R M A V A D L N Q
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q68Y21 1009 113606 M46 K D D E V F R M A V A D L N L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q03445 991 111650 Y59 D V Q S A F K Y A M L N H N L
Honey Bee Apis mellifera XP_394265 861 97699
Nematode Worm Caenorhab. elegans Q10914 977 111770 L48 A I I E M L R L A E M T F N A
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 26.7 99.6 92.2 N.A. 97.6 97.7 N.A. 92.6 93.3 N.A. 81.8 N.A. 21 27 22.8 N.A.
Protein Similarity: 100 46 99.9 93.6 N.A. 99 99.1 N.A. 96.6 97.3 N.A. 90.4 N.A. 41.6 46.5 44.1 N.A.
P-Site Identity: 100 13.3 100 0 N.A. 100 100 N.A. 86.6 80 N.A. 80 N.A. 20 0 26.6 N.A.
P-Site Similarity: 100 33.3 100 26.6 N.A. 100 100 N.A. 86.6 86.6 N.A. 80 N.A. 40 0 33.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 0 0 0 9 0 9 0 84 0 25 0 0 0 9 % A
% Cys: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % C
% Asp: 9 59 50 0 0 0 0 0 0 0 0 59 0 0 0 % D
% Glu: 0 17 9 67 0 9 0 0 9 9 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 67 0 0 0 0 0 0 9 0 0 % F
% Gly: 9 0 0 0 0 0 0 0 0 0 34 0 0 9 0 % G
% His: 0 0 9 0 0 0 0 0 0 0 0 0 9 0 0 % H
% Ile: 0 9 9 9 0 9 0 0 0 0 0 0 9 0 9 % I
% Lys: 59 0 0 0 0 0 9 0 0 9 0 0 0 0 0 % K
% Leu: 0 0 0 9 9 9 0 17 0 9 9 0 59 0 17 % L
% Met: 9 0 0 0 9 0 0 17 0 9 17 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 9 17 0 84 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 9 0 0 0 0 0 0 0 0 0 9 0 50 % Q
% Arg: 0 0 9 0 0 0 67 0 0 0 0 9 0 0 9 % R
% Ser: 0 0 0 9 9 0 0 0 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 9 34 0 0 0 9 0 0 0 % T
% Val: 0 9 0 0 59 0 0 9 0 59 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _