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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FIBP All Species: 6.06
Human Site: S224 Identified Species: 13.33
UniProt: O43427 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43427 NP_004205.2 364 41878 S224 E A P T D P D S Q M D D M D M
Chimpanzee Pan troglodytes XP_001170285 349 40242 M221 S Q M D D M D M D L D K E F L
Rhesus Macaque Macaca mulatta XP_001112432 364 41888 S224 E A P I D L D S Q M D D M D M
Dog Lupus familis XP_533228 412 46807 V279 S Q V D D M D V D L D K E F L
Cat Felis silvestris
Mouse Mus musculus Q9JI19 357 41186 V224 S Q V D D M D V D L D K E F L
Rat Rattus norvegicus NP_758837 357 41291 V224 S H M D D M D V D L D K E F L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis NP_001090040 356 41131 D224 V A D D M D M D L D K E F L Q
Zebra Danio Brachydanio rerio NP_956703 357 41368 V224 S M M E D M D V D L D K E F L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_996123 397 46727 T262 T G P E Y Y D T E M D K E F L
Honey Bee Apis mellifera XP_392194 360 42350 L225 S E Y F D T D L D R E F L L E
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_784945 364 42445 A225 S R K E D L D A D F D R E F L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 94.5 99.4 85.1 N.A. 95.3 94.5 N.A. N.A. N.A. 76.9 71.4 N.A. 40.8 46.1 N.A. 47.8
Protein Similarity: 100 95.3 99.4 86.4 N.A. 96.1 95.5 N.A. N.A. N.A. 88.7 84.6 N.A. 60.9 67.5 N.A. 69.5
P-Site Identity: 100 20 86.6 20 N.A. 20 20 N.A. N.A. N.A. 6.6 20 N.A. 26.6 13.3 N.A. 20
P-Site Similarity: 100 33.3 86.6 33.3 N.A. 33.3 33.3 N.A. N.A. N.A. 13.3 33.3 N.A. 46.6 26.6 N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 28 0 0 0 0 0 10 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 10 46 82 10 91 10 64 10 82 19 0 19 0 % D
% Glu: 19 10 0 28 0 0 0 0 10 0 10 10 64 0 10 % E
% Phe: 0 0 0 10 0 0 0 0 0 10 0 10 10 64 0 % F
% Gly: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 10 0 0 0 0 0 0 0 10 55 0 0 0 % K
% Leu: 0 0 0 0 0 19 0 10 10 46 0 0 10 19 64 % L
% Met: 0 10 28 0 10 46 10 10 0 28 0 0 19 0 19 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 28 0 0 10 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 28 0 0 0 0 0 0 19 0 0 0 0 0 10 % Q
% Arg: 0 10 0 0 0 0 0 0 0 10 0 10 0 0 0 % R
% Ser: 64 0 0 0 0 0 0 19 0 0 0 0 0 0 0 % S
% Thr: 10 0 0 10 0 10 0 10 0 0 0 0 0 0 0 % T
% Val: 10 0 19 0 0 0 0 37 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 10 0 10 10 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _