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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FIBP All Species: 29.09
Human Site: T353 Identified Species: 64
UniProt: O43427 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43427 NP_004205.2 364 41878 T353 L W D R Y M G T L R G C L L R
Chimpanzee Pan troglodytes XP_001170285 349 40242 T338 L W D R Y M G T L R G C L L R
Rhesus Macaque Macaca mulatta XP_001112432 364 41888 T353 L W D R Y M G T L R G C L L R
Dog Lupus familis XP_533228 412 46807 T401 L W D R Y M G T L R G C L L R
Cat Felis silvestris
Mouse Mus musculus Q9JI19 357 41186 T346 L W D R Y M G T L R G C L L R
Rat Rattus norvegicus NP_758837 357 41291 T346 L W D R H M G T L R G C L L R
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis NP_001090040 356 41131 T345 L W E R Y M G T L R S C L L K
Zebra Danio Brachydanio rerio NP_956703 357 41368 V346 V W T R Y M G V I K S C I L R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_996123 397 46727 Y383 T R C L W D R Y M Q V I T I C
Honey Bee Apis mellifera XP_392194 360 42350 Y346 S R D A F E R Y M T V V T C C
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_784945 364 42445 R349 R L H S T L Q R Y M S T L K K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 94.5 99.4 85.1 N.A. 95.3 94.5 N.A. N.A. N.A. 76.9 71.4 N.A. 40.8 46.1 N.A. 47.8
Protein Similarity: 100 95.3 99.4 86.4 N.A. 96.1 95.5 N.A. N.A. N.A. 88.7 84.6 N.A. 60.9 67.5 N.A. 69.5
P-Site Identity: 100 100 100 100 N.A. 100 93.3 N.A. N.A. N.A. 80 53.3 N.A. 0 6.6 N.A. 6.6
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. N.A. N.A. 93.3 80 N.A. 26.6 20 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 10 0 0 0 0 0 0 0 0 73 0 10 19 % C
% Asp: 0 0 64 0 0 10 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 10 0 0 10 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 73 0 0 0 55 0 0 0 0 % G
% His: 0 0 10 0 10 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 10 0 0 10 10 10 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 10 0 0 0 10 19 % K
% Leu: 64 10 0 10 0 10 0 0 64 0 0 0 73 73 0 % L
% Met: 0 0 0 0 0 73 0 0 19 10 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 10 0 0 10 0 0 0 0 0 % Q
% Arg: 10 19 0 73 0 0 19 10 0 64 0 0 0 0 64 % R
% Ser: 10 0 0 10 0 0 0 0 0 0 28 0 0 0 0 % S
% Thr: 10 0 10 0 10 0 0 64 0 10 0 10 19 0 0 % T
% Val: 10 0 0 0 0 0 0 10 0 0 19 10 0 0 0 % V
% Trp: 0 73 0 0 10 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 64 0 0 19 10 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _