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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EIF4G3
All Species:
13.94
Human Site:
S289
Identified Species:
76.67
UniProt:
O43432
Number Species:
4
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43432
NP_003751.2
1585
176652
S289
P
T
S
S
A
L
S
S
Q
P
I
F
T
T
A
Chimpanzee
Pan troglodytes
XP_001165083
1923
210801
S627
P
T
S
S
A
V
S
S
Q
P
I
F
T
T
A
Rhesus Macaque
Macaca mulatta
XP_001093301
1504
163783
T294
A
R
T
A
S
T
P
T
P
P
Q
T
G
G
G
Dog
Lupus familis
XP_535377
1722
190693
S429
P
T
S
A
A
L
S
S
Q
P
I
F
A
S
A
Cat
Felis silvestris
Mouse
Mus musculus
Q80XI3
1579
174872
S289
P
M
S
A
A
L
S
S
Q
P
L
F
T
A
E
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
82
40.8
85.7
N.A.
86.8
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
82.2
53.4
88.2
N.A.
91.7
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
6.6
80
N.A.
66.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
33.3
93.3
N.A.
80
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
20
0
0
60
80
0
0
0
0
0
0
0
20
20
60
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
20
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
80
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
20
20
20
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
60
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
60
0
0
0
0
20
0
0
0
0
% L
% Met:
0
20
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
80
0
0
0
0
0
20
0
20
100
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
80
0
20
0
0
0
0
% Q
% Arg:
0
20
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
80
40
20
0
80
80
0
0
0
0
0
20
0
% S
% Thr:
0
60
20
0
0
20
0
20
0
0
0
20
60
40
0
% T
% Val:
0
0
0
0
0
20
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _