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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CBFA2T2 All Species: 22.12
Human Site: T274 Identified Species: 81.11
UniProt: O43439 Number Species: 6
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43439 NP_001028171.1 604 67133 T274 P R H S P A L T V P L M N P G
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001103894 614 67909 T284 P R H S P A L T V P L M N P G
Dog Lupus familis XP_851097 575 63926 T245 P R H S P A L T V P L M N P G
Cat Felis silvestris
Mouse Mus musculus O70374 594 65886 T265 P R H S P A L T V P L M N P G
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509338 657 72068 T332 P R H S P A L T L P L M N P G
Chicken Gallus gallus Q5F3B1 591 64855 G273 Q R Y S P S N G L S H P P N G
Frog Xenopus laevis Q9IAB2 586 65036 S260 P R H S P A L S L P L V N S T
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 95.7 92.7 N.A. 93.5 N.A. N.A. 79.3 57.7 76.1 N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 N.A. 96.4 94 N.A. 95.1 N.A. N.A. 84.9 72.3 85.7 N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 N.A. 100 100 N.A. 100 N.A. N.A. 93.3 26.6 66.6 N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 N.A. 100 100 N.A. 100 N.A. N.A. 100 46.6 86.6 N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 86 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 15 0 0 0 0 0 0 86 % G
% His: 0 0 86 0 0 0 0 0 0 0 15 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 86 0 43 0 86 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 72 0 0 0 % M
% Asn: 0 0 0 0 0 0 15 0 0 0 0 0 86 15 0 % N
% Pro: 86 0 0 0 100 0 0 0 0 86 0 15 15 72 0 % P
% Gln: 15 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 100 0 15 0 15 0 15 0 0 0 15 0 % S
% Thr: 0 0 0 0 0 0 0 72 0 0 0 0 0 0 15 % T
% Val: 0 0 0 0 0 0 0 0 58 0 0 15 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 15 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _