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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SUV39H1
All Species:
18.79
Human Site:
S280
Identified Species:
34.44
UniProt:
O43463
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43463
NP_003164.1
412
47907
S280
Y
V
G
E
I
I
T
S
E
E
A
E
R
R
G
Chimpanzee
Pan troglodytes
XP_521048
334
39076
Y207
A
S
L
H
K
F
A
Y
N
D
Q
G
Q
V
R
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_548987
412
47846
S280
Y
V
G
E
I
I
T
S
E
E
A
E
R
R
G
Cat
Felis silvestris
Mouse
Mus musculus
O54864
412
47736
S280
Y
V
G
E
I
I
T
S
E
E
A
E
R
R
G
Rat
Rattus norvegicus
Q5I0M0
315
35011
A188
R
R
I
H
L
Q
T
A
H
D
P
N
Y
I
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515560
415
47688
V282
K
I
K
R
M
S
F
V
M
E
Y
V
G
E
V
Chicken
Gallus gallus
Q5F3W5
407
46641
E279
F
V
M
E
Y
V
G
E
V
I
T
S
E
E
A
Frog
Xenopus laevis
Q6NRE8
421
48563
S289
Y
V
G
E
I
I
T
S
E
E
A
E
R
R
G
Zebra Danio
Brachydanio rerio
Q6DGD3
411
47452
T279
Y
L
G
E
I
I
T
T
D
E
A
E
Q
R
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P45975
635
71885
A497
W
G
V
R
A
A
T
A
L
R
K
G
E
F
V
Honey Bee
Apis mellifera
NP_001035367
683
78686
N532
Y
V
G
E
V
I
T
N
E
E
A
E
K
R
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782949
324
36247
E197
K
K
N
S
F
V
M
E
Y
V
G
E
V
I
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q8X225
331
37553
R204
T
S
E
E
A
D
R
R
R
A
E
S
T
I
A
Conservation
Percent
Protein Identity:
100
78.8
N.A.
99.2
N.A.
95.3
26.2
N.A.
59.2
59.4
75.5
62.6
N.A.
30.5
28.8
N.A.
45.1
Protein Similarity:
100
79.6
N.A.
99.2
N.A.
98.3
40.2
N.A.
74.4
74.2
85
77.6
N.A.
44
41.4
N.A.
56.5
P-Site Identity:
100
0
N.A.
100
N.A.
100
6.6
N.A.
6.6
13.3
100
73.3
N.A.
6.6
80
N.A.
6.6
P-Site Similarity:
100
13.3
N.A.
100
N.A.
100
26.6
N.A.
20
26.6
100
100
N.A.
20
100
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
26.9
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
43.4
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
16
8
8
16
0
8
47
0
0
0
16
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
8
0
0
8
16
0
0
0
0
0
% D
% Glu:
0
0
8
62
0
0
0
16
39
54
8
54
16
16
0
% E
% Phe:
8
0
0
0
8
8
8
0
0
0
0
0
0
8
0
% F
% Gly:
0
8
47
0
0
0
8
0
0
0
8
16
8
0
47
% G
% His:
0
0
0
16
0
0
0
0
8
0
0
0
0
0
0
% H
% Ile:
0
8
8
0
39
47
0
0
0
8
0
0
0
24
8
% I
% Lys:
16
8
8
0
8
0
0
0
0
0
8
0
8
0
0
% K
% Leu:
0
8
8
0
8
0
0
0
8
0
0
0
0
0
0
% L
% Met:
0
0
8
0
8
0
8
0
8
0
0
0
0
0
0
% M
% Asn:
0
0
8
0
0
0
0
8
8
0
0
8
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% P
% Gln:
0
0
0
0
0
8
0
0
0
0
8
0
16
0
0
% Q
% Arg:
8
8
0
16
0
0
8
8
8
8
0
0
31
47
8
% R
% Ser:
0
16
0
8
0
8
0
31
0
0
0
16
0
0
0
% S
% Thr:
8
0
0
0
0
0
62
8
0
0
8
0
8
0
8
% T
% Val:
0
47
8
0
8
16
0
8
8
8
0
8
8
8
16
% V
% Trp:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
47
0
0
0
8
0
0
8
8
0
8
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _