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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SUV39H1
All Species:
28.79
Human Site:
S70
Identified Species:
52.78
UniProt:
O43463
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43463
NP_003164.1
412
47907
S70
K
W
R
G
Y
P
D
S
E
S
T
W
E
P
R
Chimpanzee
Pan troglodytes
XP_521048
334
39076
C25
W
N
Q
L
Q
D
L
C
R
L
A
K
L
S
C
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_548987
412
47846
S70
K
W
R
G
Y
P
D
S
E
S
T
W
E
P
R
Cat
Felis silvestris
Mouse
Mus musculus
O54864
412
47736
S70
K
W
R
G
Y
P
D
S
E
N
T
W
E
P
R
Rat
Rattus norvegicus
Q5I0M0
315
35011
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515560
415
47688
S79
K
W
K
G
W
P
E
S
T
N
T
W
E
P
L
Chicken
Gallus gallus
Q5F3W5
407
46641
S70
K
W
K
G
W
P
E
S
S
N
T
W
E
P
Q
Frog
Xenopus laevis
Q6NRE8
421
48563
S73
K
W
K
Y
Y
P
D
S
E
S
T
W
E
P
R
Zebra Danio
Brachydanio rerio
Q6DGD3
411
47452
S70
K
W
K
G
Y
E
E
S
E
N
T
W
E
P
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P45975
635
71885
S246
K
W
L
G
Y
H
D
S
E
N
T
W
E
S
L
Honey Bee
Apis mellifera
NP_001035367
683
78686
K271
K
W
K
N
W
D
L
K
Y
N
T
W
E
P
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782949
324
36247
V15
E
F
D
V
E
E
I
V
D
Y
Q
K
D
G
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q8X225
331
37553
K22
P
D
A
N
P
K
E
K
K
N
C
H
W
C
Q
Conservation
Percent
Protein Identity:
100
78.8
N.A.
99.2
N.A.
95.3
26.2
N.A.
59.2
59.4
75.5
62.6
N.A.
30.5
28.8
N.A.
45.1
Protein Similarity:
100
79.6
N.A.
99.2
N.A.
98.3
40.2
N.A.
74.4
74.2
85
77.6
N.A.
44
41.4
N.A.
56.5
P-Site Identity:
100
0
N.A.
100
N.A.
93.3
0
N.A.
60
60
86.6
66.6
N.A.
66.6
40
N.A.
0
P-Site Similarity:
100
6.6
N.A.
100
N.A.
100
0
N.A.
86.6
93.3
93.3
86.6
N.A.
73.3
60
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
26.9
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
43.4
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
0
0
0
0
0
8
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
8
0
0
8
8
% C
% Asp:
0
8
8
0
0
16
39
0
8
0
0
0
8
0
0
% D
% Glu:
8
0
0
0
8
16
31
0
47
0
0
0
70
0
0
% E
% Phe:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
54
0
0
0
0
0
0
0
0
0
8
0
% G
% His:
0
0
0
0
0
8
0
0
0
0
0
8
0
0
0
% H
% Ile:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
8
% I
% Lys:
70
0
39
0
0
8
0
16
8
0
0
16
0
0
0
% K
% Leu:
0
0
8
8
0
0
16
0
0
8
0
0
8
0
24
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
16
0
0
0
0
0
54
0
0
0
0
8
% N
% Pro:
8
0
0
0
8
47
0
0
0
0
0
0
0
62
0
% P
% Gln:
0
0
8
0
8
0
0
0
0
0
8
0
0
0
16
% Q
% Arg:
0
0
24
0
0
0
0
0
8
0
0
0
0
0
31
% R
% Ser:
0
0
0
0
0
0
0
62
8
24
0
0
0
16
0
% S
% Thr:
0
0
0
0
0
0
0
0
8
0
70
0
0
0
0
% T
% Val:
0
0
0
8
0
0
0
8
0
0
0
0
0
0
0
% V
% Trp:
8
70
0
0
24
0
0
0
0
0
0
70
8
0
0
% W
% Tyr:
0
0
0
8
47
0
0
0
8
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _