KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SUV39H1
All Species:
9.7
Human Site:
T146
Identified Species:
17.78
UniProt:
O43463
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43463
NP_003164.1
412
47907
T146
R
S
H
L
G
R
I
T
V
E
N
E
V
D
L
Chimpanzee
Pan troglodytes
XP_521048
334
39076
E77
P
D
S
E
S
T
W
E
P
R
Q
N
L
K
C
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_548987
412
47846
T146
R
S
H
L
G
R
I
T
V
E
N
E
V
D
L
Cat
Felis silvestris
Mouse
Mus musculus
O54864
412
47736
T146
R
S
H
L
G
R
I
T
V
E
N
E
V
D
L
Rat
Rattus norvegicus
Q5I0M0
315
35011
H58
P
F
Q
Y
T
P
D
H
V
A
G
P
G
V
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515560
415
47688
R144
K
Q
R
I
A
L
Q
R
W
Q
E
E
L
N
R
Chicken
Gallus gallus
Q5F3W5
407
46641
K144
K
E
E
L
N
R
K
K
N
H
K
G
M
I
L
Frog
Xenopus laevis
Q6NRE8
421
48563
L156
R
S
H
L
G
L
I
L
V
E
N
E
V
D
L
Zebra Danio
Brachydanio rerio
Q6DGD3
411
47452
F145
C
W
H
K
G
R
I
F
V
S
N
E
V
D
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P45975
635
71885
K353
R
A
Q
F
V
R
R
K
Q
L
A
D
L
A
L
Honey Bee
Apis mellifera
NP_001035367
683
78686
R399
T
K
G
K
P
L
I
R
V
E
N
I
I
D
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782949
324
36247
A67
N
S
K
C
Q
N
E
A
P
I
T
I
V
N
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q8X225
331
37553
S74
N
V
P
V
A
D
Q
S
F
R
V
G
C
S
C
Conservation
Percent
Protein Identity:
100
78.8
N.A.
99.2
N.A.
95.3
26.2
N.A.
59.2
59.4
75.5
62.6
N.A.
30.5
28.8
N.A.
45.1
Protein Similarity:
100
79.6
N.A.
99.2
N.A.
98.3
40.2
N.A.
74.4
74.2
85
77.6
N.A.
44
41.4
N.A.
56.5
P-Site Identity:
100
0
N.A.
100
N.A.
100
6.6
N.A.
6.6
20
86.6
60
N.A.
20
40
N.A.
13.3
P-Site Similarity:
100
6.6
N.A.
100
N.A.
100
6.6
N.A.
40
33.3
86.6
66.6
N.A.
40
46.6
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
26.9
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
43.4
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
16
0
0
8
0
8
8
0
0
8
0
% A
% Cys:
8
0
0
8
0
0
0
0
0
0
0
0
8
0
16
% C
% Asp:
0
8
0
0
0
8
8
0
0
0
0
8
0
47
8
% D
% Glu:
0
8
8
8
0
0
8
8
0
39
8
47
0
0
0
% E
% Phe:
0
8
0
8
0
0
0
8
8
0
0
0
0
0
0
% F
% Gly:
0
0
8
0
39
0
0
0
0
0
8
16
8
0
0
% G
% His:
0
0
39
0
0
0
0
8
0
8
0
0
0
0
0
% H
% Ile:
0
0
0
8
0
0
47
0
0
8
0
16
8
8
0
% I
% Lys:
16
8
8
16
0
0
8
16
0
0
8
0
0
8
0
% K
% Leu:
0
0
0
39
0
24
0
8
0
8
0
0
24
0
54
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
8
% M
% Asn:
16
0
0
0
8
8
0
0
8
0
47
8
0
16
8
% N
% Pro:
16
0
8
0
8
8
0
0
16
0
0
8
0
0
0
% P
% Gln:
0
8
16
0
8
0
16
0
8
8
8
0
0
0
0
% Q
% Arg:
39
0
8
0
0
47
8
16
0
16
0
0
0
0
8
% R
% Ser:
0
39
8
0
8
0
0
8
0
8
0
0
0
8
0
% S
% Thr:
8
0
0
0
8
8
0
24
0
0
8
0
0
0
0
% T
% Val:
0
8
0
8
8
0
0
0
54
0
8
0
47
8
0
% V
% Trp:
0
8
0
0
0
0
8
0
8
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _