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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SUV39H1
All Species:
19.09
Human Site:
Y117
Identified Species:
35
UniProt:
O43463
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43463
NP_003164.1
412
47907
Y117
L
D
P
S
L
A
N
Y
L
V
Q
K
A
K
Q
Chimpanzee
Pan troglodytes
XP_521048
334
39076
I56
Y
L
C
D
Y
K
K
I
R
E
Q
E
Y
Y
L
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_548987
412
47846
Y117
L
D
P
S
L
A
N
Y
L
V
Q
K
A
K
Q
Cat
Felis silvestris
Mouse
Mus musculus
O54864
412
47736
Y117
L
D
P
N
L
A
N
Y
L
V
Q
K
A
K
Q
Rat
Rattus norvegicus
Q5I0M0
315
35011
P37
A
C
G
L
E
N
L
P
V
S
L
W
P
L
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515560
415
47688
N120
K
V
I
T
L
K
N
N
V
K
I
L
R
P
A
Chicken
Gallus gallus
Q5F3W5
407
46641
Y122
L
K
P
A
V
A
D
Y
I
V
K
K
A
K
Q
Frog
Xenopus laevis
Q6NRE8
421
48563
Y127
L
D
Q
S
L
S
H
Y
L
V
L
K
A
K
Q
Zebra Danio
Brachydanio rerio
Q6DGD3
411
47452
F116
L
S
G
P
I
I
S
F
L
R
Q
K
A
T
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P45975
635
71885
D313
E
P
L
N
L
Q
I
D
L
I
L
L
A
Q
Y
Honey Bee
Apis mellifera
NP_001035367
683
78686
I341
V
E
S
N
T
M
F
I
N
I
L
K
F
L
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782949
324
36247
S46
A
L
T
D
V
L
K
S
L
V
K
K
E
L
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q8X225
331
37553
N53
R
E
D
D
A
F
L
N
P
N
F
R
F
I
D
Conservation
Percent
Protein Identity:
100
78.8
N.A.
99.2
N.A.
95.3
26.2
N.A.
59.2
59.4
75.5
62.6
N.A.
30.5
28.8
N.A.
45.1
Protein Similarity:
100
79.6
N.A.
99.2
N.A.
98.3
40.2
N.A.
74.4
74.2
85
77.6
N.A.
44
41.4
N.A.
56.5
P-Site Identity:
100
6.6
N.A.
100
N.A.
93.3
0
N.A.
13.3
60
73.3
40
N.A.
20
6.6
N.A.
20
P-Site Similarity:
100
13.3
N.A.
100
N.A.
100
6.6
N.A.
26.6
93.3
86.6
60
N.A.
40
40
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
26.9
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
43.4
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
0
0
8
8
31
0
0
0
0
0
0
54
0
8
% A
% Cys:
0
8
8
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
31
8
24
0
0
8
8
0
0
0
0
0
0
8
% D
% Glu:
8
16
0
0
8
0
0
0
0
8
0
8
8
0
0
% E
% Phe:
0
0
0
0
0
8
8
8
0
0
8
0
16
0
0
% F
% Gly:
0
0
16
0
0
0
0
0
0
0
0
0
0
0
8
% G
% His:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
0
8
8
8
16
8
16
8
0
0
8
0
% I
% Lys:
8
8
0
0
0
16
16
0
0
8
16
62
0
39
16
% K
% Leu:
47
16
8
8
47
8
16
0
54
0
31
16
0
24
8
% L
% Met:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
24
0
8
31
16
8
8
0
0
0
0
0
% N
% Pro:
0
8
31
8
0
0
0
8
8
0
0
0
8
8
0
% P
% Gln:
0
0
8
0
0
8
0
0
0
0
39
0
0
8
47
% Q
% Arg:
8
0
0
0
0
0
0
0
8
8
0
8
8
0
0
% R
% Ser:
0
8
8
24
0
8
8
8
0
8
0
0
0
0
0
% S
% Thr:
0
0
8
8
8
0
0
0
0
0
0
0
0
8
0
% T
% Val:
8
8
0
0
16
0
0
0
16
47
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% W
% Tyr:
8
0
0
0
8
0
0
39
0
0
0
0
8
8
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _