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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SUV39H1 All Species: 19.09
Human Site: Y117 Identified Species: 35
UniProt: O43463 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43463 NP_003164.1 412 47907 Y117 L D P S L A N Y L V Q K A K Q
Chimpanzee Pan troglodytes XP_521048 334 39076 I56 Y L C D Y K K I R E Q E Y Y L
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_548987 412 47846 Y117 L D P S L A N Y L V Q K A K Q
Cat Felis silvestris
Mouse Mus musculus O54864 412 47736 Y117 L D P N L A N Y L V Q K A K Q
Rat Rattus norvegicus Q5I0M0 315 35011 P37 A C G L E N L P V S L W P L G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515560 415 47688 N120 K V I T L K N N V K I L R P A
Chicken Gallus gallus Q5F3W5 407 46641 Y122 L K P A V A D Y I V K K A K Q
Frog Xenopus laevis Q6NRE8 421 48563 Y127 L D Q S L S H Y L V L K A K Q
Zebra Danio Brachydanio rerio Q6DGD3 411 47452 F116 L S G P I I S F L R Q K A T Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P45975 635 71885 D313 E P L N L Q I D L I L L A Q Y
Honey Bee Apis mellifera NP_001035367 683 78686 I341 V E S N T M F I N I L K F L K
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_782949 324 36247 S46 A L T D V L K S L V K K E L K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q8X225 331 37553 N53 R E D D A F L N P N F R F I D
Conservation
Percent
Protein Identity: 100 78.8 N.A. 99.2 N.A. 95.3 26.2 N.A. 59.2 59.4 75.5 62.6 N.A. 30.5 28.8 N.A. 45.1
Protein Similarity: 100 79.6 N.A. 99.2 N.A. 98.3 40.2 N.A. 74.4 74.2 85 77.6 N.A. 44 41.4 N.A. 56.5
P-Site Identity: 100 6.6 N.A. 100 N.A. 93.3 0 N.A. 13.3 60 73.3 40 N.A. 20 6.6 N.A. 20
P-Site Similarity: 100 13.3 N.A. 100 N.A. 100 6.6 N.A. 26.6 93.3 86.6 60 N.A. 40 40 N.A. 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. 26.9
Protein Similarity: N.A. N.A. N.A. N.A. N.A. 43.4
P-Site Identity: N.A. N.A. N.A. N.A. N.A. 0
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. 13.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 16 0 0 8 8 31 0 0 0 0 0 0 54 0 8 % A
% Cys: 0 8 8 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 31 8 24 0 0 8 8 0 0 0 0 0 0 8 % D
% Glu: 8 16 0 0 8 0 0 0 0 8 0 8 8 0 0 % E
% Phe: 0 0 0 0 0 8 8 8 0 0 8 0 16 0 0 % F
% Gly: 0 0 16 0 0 0 0 0 0 0 0 0 0 0 8 % G
% His: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 8 0 8 8 8 16 8 16 8 0 0 8 0 % I
% Lys: 8 8 0 0 0 16 16 0 0 8 16 62 0 39 16 % K
% Leu: 47 16 8 8 47 8 16 0 54 0 31 16 0 24 8 % L
% Met: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 24 0 8 31 16 8 8 0 0 0 0 0 % N
% Pro: 0 8 31 8 0 0 0 8 8 0 0 0 8 8 0 % P
% Gln: 0 0 8 0 0 8 0 0 0 0 39 0 0 8 47 % Q
% Arg: 8 0 0 0 0 0 0 0 8 8 0 8 8 0 0 % R
% Ser: 0 8 8 24 0 8 8 8 0 8 0 0 0 0 0 % S
% Thr: 0 0 8 8 8 0 0 0 0 0 0 0 0 8 0 % T
% Val: 8 8 0 0 16 0 0 0 16 47 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % W
% Tyr: 8 0 0 0 8 0 0 39 0 0 0 0 8 8 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _