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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SUV39H1 All Species: 16.97
Human Site: Y205 Identified Species: 31.11
UniProt: O43463 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43463 NP_003164.1 412 47907 Y205 A S L H K F A Y N D Q G Q V R
Chimpanzee Pan troglodytes XP_521048 334 39076 R132 K Q R R A L R R W E Q E L N A
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_548987 412 47846 Y205 A S L H K F A Y N D Q G Q V R
Cat Felis silvestris
Mouse Mus musculus O54864 412 47736 Y205 A S L H K F A Y N D Q G Q V R
Rat Rattus norvegicus Q5I0M0 315 35011 A113 V G S E A K Y A K P V F E C N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515560 415 47688 C207 D C F F E K C C P A E A G V H
Chicken Gallus gallus Q5F3W5 407 46641 F204 C C P K E A G F I L A Y N K Q
Frog Xenopus laevis Q6NRE8 421 48563 Y214 A F Q H K K A Y N N E G Q V K
Zebra Danio Brachydanio rerio Q6DGD3 411 47452 Y204 L L K F R R A Y N E S R R V K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P45975 635 71885 T422 T E D T E E C T A S T K C C A
Honey Bee Apis mellifera NP_001035367 683 78686 Y457 Q D D G L C P Y T L K H K I R
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_782949 324 36247 Q122 A E S R C C P Q N G G V K F A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q8X225 331 37553 D129 A K K G L L R D R V L Q S Q E
Conservation
Percent
Protein Identity: 100 78.8 N.A. 99.2 N.A. 95.3 26.2 N.A. 59.2 59.4 75.5 62.6 N.A. 30.5 28.8 N.A. 45.1
Protein Similarity: 100 79.6 N.A. 99.2 N.A. 98.3 40.2 N.A. 74.4 74.2 85 77.6 N.A. 44 41.4 N.A. 56.5
P-Site Identity: 100 6.6 N.A. 100 N.A. 100 0 N.A. 6.6 0 60 26.6 N.A. 0 13.3 N.A. 13.3
P-Site Similarity: 100 13.3 N.A. 100 N.A. 100 6.6 N.A. 20 20 80 53.3 N.A. 6.6 33.3 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. 26.9
Protein Similarity: N.A. N.A. N.A. N.A. N.A. 43.4
P-Site Identity: N.A. N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. 6.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 47 0 0 0 16 8 39 8 8 8 8 8 0 0 24 % A
% Cys: 8 16 0 0 8 16 16 8 0 0 0 0 8 16 0 % C
% Asp: 8 8 16 0 0 0 0 8 0 24 0 0 0 0 0 % D
% Glu: 0 16 0 8 24 8 0 0 0 16 16 8 8 0 8 % E
% Phe: 0 8 8 16 0 24 0 8 0 0 0 8 0 8 0 % F
% Gly: 0 8 0 16 0 0 8 0 0 8 8 31 8 0 0 % G
% His: 0 0 0 31 0 0 0 0 0 0 0 8 0 0 8 % H
% Ile: 0 0 0 0 0 0 0 0 8 0 0 0 0 8 0 % I
% Lys: 8 8 16 8 31 24 0 0 8 0 8 8 16 8 16 % K
% Leu: 8 8 24 0 16 16 0 0 0 16 8 0 8 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 47 8 0 0 8 8 8 % N
% Pro: 0 0 8 0 0 0 16 0 8 8 0 0 0 0 0 % P
% Gln: 8 8 8 0 0 0 0 8 0 0 31 8 31 8 8 % Q
% Arg: 0 0 8 16 8 8 16 8 8 0 0 8 8 0 31 % R
% Ser: 0 24 16 0 0 0 0 0 0 8 8 0 8 0 0 % S
% Thr: 8 0 0 8 0 0 0 8 8 0 8 0 0 0 0 % T
% Val: 8 0 0 0 0 0 0 0 0 8 8 8 0 47 0 % V
% Trp: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 8 47 0 0 0 8 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _