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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SUV39H1
All Species:
21.82
Human Site:
Y290
Identified Species:
40
UniProt:
O43463
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43463
NP_003164.1
412
47907
Y290
A
E
R
R
G
Q
I
Y
D
R
Q
G
A
T
Y
Chimpanzee
Pan troglodytes
XP_521048
334
39076
A217
Q
G
Q
V
R
L
R
A
G
L
P
I
Y
E
C
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_548987
412
47846
Y290
A
E
R
R
G
Q
I
Y
D
R
Q
G
A
T
Y
Cat
Felis silvestris
Mouse
Mus musculus
O54864
412
47736
Y290
A
E
R
R
G
Q
I
Y
D
R
Q
G
A
T
Y
Rat
Rattus norvegicus
Q5I0M0
315
35011
R198
P
N
Y
I
I
A
L
R
E
H
T
Y
N
G
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515560
415
47688
S292
Y
V
G
E
V
I
T
S
E
E
A
E
R
R
G
Chicken
Gallus gallus
Q5F3W5
407
46641
R289
T
S
E
E
A
E
R
R
G
Q
F
Y
D
N
Q
Frog
Xenopus laevis
Q6NRE8
421
48563
Y299
A
E
R
R
G
Q
I
Y
D
R
Q
G
T
T
Y
Zebra Danio
Brachydanio rerio
Q6DGD3
411
47452
Y289
A
E
Q
R
G
V
L
Y
D
K
Q
G
V
T
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P45975
635
71885
Y507
K
G
E
F
V
C
E
Y
I
G
E
I
I
T
S
Honey Bee
Apis mellifera
NP_001035367
683
78686
Y542
A
E
K
R
G
K
E
Y
D
A
A
G
R
T
Y
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782949
324
36247
E207
G
E
V
I
T
S
E
E
A
E
R
R
G
K
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q8X225
331
37553
K214
E
S
T
I
A
R
R
K
D
V
Y
L
F
A
L
Conservation
Percent
Protein Identity:
100
78.8
N.A.
99.2
N.A.
95.3
26.2
N.A.
59.2
59.4
75.5
62.6
N.A.
30.5
28.8
N.A.
45.1
Protein Similarity:
100
79.6
N.A.
99.2
N.A.
98.3
40.2
N.A.
74.4
74.2
85
77.6
N.A.
44
41.4
N.A.
56.5
P-Site Identity:
100
0
N.A.
100
N.A.
100
0
N.A.
0
0
93.3
66.6
N.A.
13.3
60
N.A.
6.6
P-Site Similarity:
100
6.6
N.A.
100
N.A.
100
13.3
N.A.
6.6
13.3
93.3
86.6
N.A.
20
73.3
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
26.9
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
43.4
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
47
0
0
0
16
8
0
8
8
8
16
0
24
8
0
% A
% Cys:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
8
% C
% Asp:
0
0
0
0
0
0
0
0
54
0
0
0
8
0
0
% D
% Glu:
8
54
16
16
0
8
24
8
16
16
8
8
0
8
0
% E
% Phe:
0
0
0
8
0
0
0
0
0
0
8
0
8
0
0
% F
% Gly:
8
16
8
0
47
0
0
0
16
8
0
47
8
8
8
% G
% His:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% H
% Ile:
0
0
0
24
8
8
31
0
8
0
0
16
8
0
8
% I
% Lys:
8
0
8
0
0
8
0
8
0
8
0
0
0
8
0
% K
% Leu:
0
0
0
0
0
8
16
0
0
8
0
8
0
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
0
0
0
0
0
0
0
0
8
8
0
% N
% Pro:
8
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% P
% Gln:
8
0
16
0
0
31
0
0
0
8
39
0
0
0
16
% Q
% Arg:
0
0
31
47
8
8
24
16
0
31
8
8
16
8
0
% R
% Ser:
0
16
0
0
0
8
0
8
0
0
0
0
0
0
8
% S
% Thr:
8
0
8
0
8
0
8
0
0
0
8
0
8
54
0
% T
% Val:
0
8
8
8
16
8
0
0
0
8
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
8
0
0
0
0
54
0
0
8
16
8
0
47
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _