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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KLF4
All Species:
1.52
Human Site:
S295
Identified Species:
3.33
UniProt:
O43474
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43474
NP_004226.3
513
54671
S295
L
G
A
G
P
P
L
S
N
G
H
R
P
A
A
Chimpanzee
Pan troglodytes
Q19A40
323
33082
S121
F
S
D
P
I
P
C
S
V
Q
T
P
C
S
E
Rhesus Macaque
Macaca mulatta
NP_001136265
479
51042
K278
P
R
T
C
P
K
I
K
Q
E
A
V
S
S
C
Dog
Lupus familis
XP_538779
390
40599
V189
N
L
A
D
I
N
D
V
S
P
S
G
G
F
V
Cat
Felis silvestris
Mouse
Mus musculus
Q60793
483
51862
C282
K
Q
E
A
V
P
S
C
T
V
S
R
S
L
E
Rat
Rattus norvegicus
Q9ET58
351
37295
A150
R
G
L
K
L
E
G
A
L
G
A
T
G
A
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508044
491
52596
V286
P
S
C
I
G
R
P
V
E
A
H
L
G
G
G
Chicken
Gallus gallus
Q90WR8
771
80932
Q392
I
V
Q
H
I
Q
L
Q
E
S
Q
Q
P
T
S
Frog
Xenopus laevis
NP_001080430
373
42006
S172
T
K
I
K
Q
E
G
S
T
A
C
M
M
A
Y
Zebra Danio
Brachydanio rerio
NP_001106955
396
43573
F195
K
D
A
S
A
V
P
F
A
C
P
R
I
K
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781601
390
44378
Q189
M
Q
Q
L
H
H
Q
Q
Q
Q
H
H
Q
Q
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
22
92.7
67.8
N.A.
85.3
39.3
N.A.
48.5
20.1
36.2
46.7
N.A.
N.A.
N.A.
N.A.
30.4
Protein Similarity:
100
29.6
92.9
69.4
N.A.
87.5
46
N.A.
55.7
31.9
49.3
55.9
N.A.
N.A.
N.A.
N.A.
42.1
P-Site Identity:
100
13.3
6.6
6.6
N.A.
13.3
20
N.A.
6.6
13.3
13.3
13.3
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
20
20
13.3
N.A.
13.3
26.6
N.A.
6.6
33.3
13.3
13.3
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
28
10
10
0
0
10
10
19
19
0
0
28
10
% A
% Cys:
0
0
10
10
0
0
10
10
0
10
10
0
10
0
19
% C
% Asp:
0
10
10
10
0
0
10
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
10
0
0
19
0
0
19
10
0
0
0
0
19
% E
% Phe:
10
0
0
0
0
0
0
10
0
0
0
0
0
10
0
% F
% Gly:
0
19
0
10
10
0
19
0
0
19
0
10
28
10
10
% G
% His:
0
0
0
10
10
10
0
0
0
0
28
10
0
0
0
% H
% Ile:
10
0
10
10
28
0
10
0
0
0
0
0
10
0
0
% I
% Lys:
19
10
0
19
0
10
0
10
0
0
0
0
0
10
0
% K
% Leu:
10
10
10
10
10
0
19
0
10
0
0
10
0
10
0
% L
% Met:
10
0
0
0
0
0
0
0
0
0
0
10
10
0
0
% M
% Asn:
10
0
0
0
0
10
0
0
10
0
0
0
0
0
0
% N
% Pro:
19
0
0
10
19
28
19
0
0
10
10
10
19
0
0
% P
% Gln:
0
19
19
0
10
10
10
19
19
19
10
10
10
10
19
% Q
% Arg:
10
10
0
0
0
10
0
0
0
0
0
28
0
0
0
% R
% Ser:
0
19
0
10
0
0
10
28
10
10
19
0
19
19
10
% S
% Thr:
10
0
10
0
0
0
0
0
19
0
10
10
0
10
0
% T
% Val:
0
10
0
0
10
10
0
19
10
10
0
10
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _