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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KLF4
All Species:
8.48
Human Site:
S445
Identified Species:
18.67
UniProt:
O43474
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43474
NP_004226.3
513
54671
S445
G
K
T
Y
T
K
S
S
H
L
K
A
H
L
R
Chimpanzee
Pan troglodytes
Q19A40
323
33082
L259
E
K
R
F
S
C
P
L
C
P
K
Q
F
S
R
Rhesus Macaque
Macaca mulatta
NP_001136265
479
51042
A415
T
K
S
S
H
L
K
A
H
L
R
T
H
T
G
Dog
Lupus familis
XP_538779
390
40599
E326
T
P
T
L
G
A
E
E
L
L
S
S
R
E
C
Cat
Felis silvestris
Mouse
Mus musculus
Q60793
483
51862
A419
T
K
S
S
H
L
K
A
H
L
R
T
H
T
G
Rat
Rattus norvegicus
Q9ET58
351
37295
A287
T
K
S
S
H
L
K
A
H
L
R
T
H
T
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508044
491
52596
S423
G
K
T
Y
T
K
S
S
H
L
K
A
H
L
R
Chicken
Gallus gallus
Q90WR8
771
80932
S626
G
K
V
Y
G
K
T
S
H
L
R
A
H
L
R
Frog
Xenopus laevis
NP_001080430
373
42006
A309
T
K
S
S
H
L
K
A
H
L
R
T
H
T
G
Zebra Danio
Brachydanio rerio
NP_001106955
396
43573
A332
T
K
S
S
H
L
K
A
H
H
R
T
H
T
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781601
390
44378
A326
T
K
S
S
H
L
K
A
H
M
R
T
H
T
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
22
92.7
67.8
N.A.
85.3
39.3
N.A.
48.5
20.1
36.2
46.7
N.A.
N.A.
N.A.
N.A.
30.4
Protein Similarity:
100
29.6
92.9
69.4
N.A.
87.5
46
N.A.
55.7
31.9
49.3
55.9
N.A.
N.A.
N.A.
N.A.
42.1
P-Site Identity:
100
20
26.6
13.3
N.A.
26.6
26.6
N.A.
100
73.3
26.6
20
N.A.
N.A.
N.A.
N.A.
20
P-Site Similarity:
100
33.3
46.6
20
N.A.
46.6
46.6
N.A.
100
86.6
46.6
40
N.A.
N.A.
N.A.
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
10
0
55
0
0
0
28
0
0
0
% A
% Cys:
0
0
0
0
0
10
0
0
10
0
0
0
0
0
10
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
10
0
0
0
0
0
10
10
0
0
0
0
0
10
0
% E
% Phe:
0
0
0
10
0
0
0
0
0
0
0
0
10
0
0
% F
% Gly:
28
0
0
0
19
0
0
0
0
0
0
0
0
0
55
% G
% His:
0
0
0
0
55
0
0
0
82
10
0
0
82
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
91
0
0
0
28
55
0
0
0
28
0
0
0
0
% K
% Leu:
0
0
0
10
0
55
0
10
10
73
0
0
0
28
0
% L
% Met:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
10
0
0
0
0
10
0
0
10
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% Q
% Arg:
0
0
10
0
0
0
0
0
0
0
64
0
10
0
37
% R
% Ser:
0
0
55
55
10
0
19
28
0
0
10
10
0
10
0
% S
% Thr:
64
0
28
0
19
0
10
0
0
0
0
55
0
55
0
% T
% Val:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
28
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _