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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KLF4
All Species:
4.55
Human Site:
S500
Identified Species:
10
UniProt:
O43474
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43474
NP_004226.3
513
54671
S500
Q
K
C
D
R
A
F
S
R
S
D
H
L
A
L
Chimpanzee
Pan troglodytes
Q19A40
323
33082
G314
S
A
S
G
S
G
P
G
P
A
P
S
F
T
T
Rhesus Macaque
Macaca mulatta
NP_001136265
479
51042
H470
R
A
F
S
R
S
D
H
L
A
L
H
M
K
R
Dog
Lupus familis
XP_538779
390
40599
H381
R
A
F
S
R
S
D
H
L
A
L
H
M
K
R
Cat
Felis silvestris
Mouse
Mus musculus
Q60793
483
51862
H474
R
A
F
S
R
S
D
H
L
A
L
H
M
K
R
Rat
Rattus norvegicus
Q9ET58
351
37295
H342
R
A
F
S
R
S
D
H
L
A
L
H
M
K
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508044
491
52596
S478
Q
R
C
D
R
A
F
S
R
S
D
H
L
A
L
Chicken
Gallus gallus
Q90WR8
771
80932
M681
P
E
C
S
K
R
F
M
R
S
D
H
L
A
K
Frog
Xenopus laevis
NP_001080430
373
42006
H364
R
A
F
S
R
S
D
H
L
A
L
H
M
K
R
Zebra Danio
Brachydanio rerio
NP_001106955
396
43573
H387
R
A
F
S
R
S
D
H
L
A
L
H
M
K
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781601
390
44378
H381
R
A
F
S
R
S
D
H
L
S
L
H
M
K
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
22
92.7
67.8
N.A.
85.3
39.3
N.A.
48.5
20.1
36.2
46.7
N.A.
N.A.
N.A.
N.A.
30.4
Protein Similarity:
100
29.6
92.9
69.4
N.A.
87.5
46
N.A.
55.7
31.9
49.3
55.9
N.A.
N.A.
N.A.
N.A.
42.1
P-Site Identity:
100
0
13.3
13.3
N.A.
13.3
13.3
N.A.
93.3
53.3
13.3
13.3
N.A.
N.A.
N.A.
N.A.
20
P-Site Similarity:
100
6.6
40
40
N.A.
40
40
N.A.
100
66.6
40
40
N.A.
N.A.
N.A.
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
73
0
0
0
19
0
0
0
64
0
0
0
28
0
% A
% Cys:
0
0
28
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
19
0
0
64
0
0
0
28
0
0
0
0
% D
% Glu:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
64
0
0
0
28
0
0
0
0
0
10
0
0
% F
% Gly:
0
0
0
10
0
10
0
10
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
64
0
0
0
91
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
10
0
0
10
0
0
0
0
0
0
0
0
64
10
% K
% Leu:
0
0
0
0
0
0
0
0
64
0
64
0
28
0
19
% L
% Met:
0
0
0
0
0
0
0
10
0
0
0
0
64
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
10
0
0
0
0
0
10
0
10
0
10
0
0
0
0
% P
% Gln:
19
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
64
10
0
0
82
10
0
0
28
0
0
0
0
0
64
% R
% Ser:
10
0
10
73
10
64
0
19
0
37
0
10
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
10
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _