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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KLF4 All Species: 0.3
Human Site: Y348 Identified Species: 0.67
UniProt: O43474 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43474 NP_004226.3 513 54671 Y348 H P H P G P N Y P S F L P D Q
Chimpanzee Pan troglodytes Q19A40 323 33082 F166 A P A A S G G F S G G A L G A
Rhesus Macaque Macaca mulatta NP_001136265 479 51042 E322 T T P T L G L E E V L S S R D
Dog Lupus familis XP_538779 390 40599 A233 V L K A S L S A P G S E Y G S
Cat Felis silvestris
Mouse Mus musculus Q60793 483 51862 E326 T T P T L S P E E L L N S R D
Rat Rattus norvegicus Q9ET58 351 37295 P194 P R N P F P P P F G P G P S F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508044 491 52596 M330 S L T A E E L M N S S R D C H
Chicken Gallus gallus Q90WR8 771 80932 A532 Q L H Q G E N A G S P A D I R
Frog Xenopus laevis NP_001080430 373 42006 P216 Q S Q L M C H P S L P Y A P N
Zebra Danio Brachydanio rerio NP_001106955 396 43573 S239 M L D P H A F S S G R G A R S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_781601 390 44378 H233 P P P Y S H Q H L V A P Q M T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 22 92.7 67.8 N.A. 85.3 39.3 N.A. 48.5 20.1 36.2 46.7 N.A. N.A. N.A. N.A. 30.4
Protein Similarity: 100 29.6 92.9 69.4 N.A. 87.5 46 N.A. 55.7 31.9 49.3 55.9 N.A. N.A. N.A. N.A. 42.1
P-Site Identity: 100 6.6 0 6.6 N.A. 0 20 N.A. 6.6 26.6 0 6.6 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 13.3 0 13.3 N.A. 0 26.6 N.A. 6.6 33.3 6.6 6.6 N.A. N.A. N.A. N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 10 28 0 10 0 19 0 0 10 19 19 0 10 % A
% Cys: 0 0 0 0 0 10 0 0 0 0 0 0 0 10 0 % C
% Asp: 0 0 10 0 0 0 0 0 0 0 0 0 19 10 19 % D
% Glu: 0 0 0 0 10 19 0 19 19 0 0 10 0 0 0 % E
% Phe: 0 0 0 0 10 0 10 10 10 0 10 0 0 0 10 % F
% Gly: 0 0 0 0 19 19 10 0 10 37 10 19 0 19 0 % G
% His: 10 0 19 0 10 10 10 10 0 0 0 0 0 0 10 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % I
% Lys: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 37 0 10 19 10 19 0 10 19 19 10 10 0 0 % L
% Met: 10 0 0 0 10 0 0 10 0 0 0 0 0 10 0 % M
% Asn: 0 0 10 0 0 0 19 0 10 0 0 10 0 0 10 % N
% Pro: 19 28 28 28 0 19 19 19 19 0 28 10 19 10 0 % P
% Gln: 19 0 10 10 0 0 10 0 0 0 0 0 10 0 10 % Q
% Arg: 0 10 0 0 0 0 0 0 0 0 10 10 0 28 10 % R
% Ser: 10 10 0 0 28 10 10 10 28 28 19 10 19 10 19 % S
% Thr: 19 19 10 19 0 0 0 0 0 0 0 0 0 0 10 % T
% Val: 10 0 0 0 0 0 0 0 0 19 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 10 0 0 0 10 0 0 0 10 10 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _