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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PROM1
All Species:
12.12
Human Site:
S258
Identified Species:
29.63
UniProt:
O43490
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43490
NP_006008.1
865
97202
S258
P
V
L
D
E
I
K
S
M
A
T
A
I
K
E
Chimpanzee
Pan troglodytes
XP_517115
865
97216
S258
P
V
L
D
E
I
K
S
M
A
T
A
I
K
E
Rhesus Macaque
Macaca mulatta
NP_001070888
841
94490
S258
P
V
L
D
E
I
K
S
M
A
T
A
I
K
E
Dog
Lupus familis
XP_850831
831
93500
P251
Q
L
R
P
K
V
I
P
V
L
D
D
I
K
A
Cat
Felis silvestris
Mouse
Mus musculus
O54990
867
97095
A259
P
V
L
E
E
I
K
A
M
A
T
A
I
K
Q
Rat
Rattus norvegicus
Q8CJ52
834
92822
P247
Q
L
K
S
T
V
Y
P
V
L
A
S
V
H
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515242
740
82713
N160
Q
E
G
T
D
K
L
N
A
N
L
T
D
V
K
Chicken
Gallus gallus
XP_001232165
871
96765
T259
P
A
L
D
A
A
L
T
M
A
G
A
I
R
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q9W735
826
91929
I237
G
V
I
L
G
G
R
I
H
E
E
L
G
K
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_798860
858
93747
D265
P
A
I
D
S
V
I
D
M
E
T
N
I
D
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
93.1
63.5
N.A.
60.6
26.5
N.A.
44.3
52.8
N.A.
41.7
N.A.
N.A.
N.A.
N.A.
26.9
Protein Similarity:
100
99.4
94.9
80.1
N.A.
78.7
48.3
N.A.
62.3
73.7
N.A.
63.3
N.A.
N.A.
N.A.
N.A.
45.7
P-Site Identity:
100
100
100
13.3
N.A.
80
0
N.A.
0
53.3
N.A.
20
N.A.
N.A.
N.A.
N.A.
33.3
P-Site Similarity:
100
100
100
40
N.A.
100
33.3
N.A.
20
66.6
N.A.
33.3
N.A.
N.A.
N.A.
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
20
0
0
10
10
0
10
10
50
10
50
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
50
10
0
0
10
0
0
10
10
10
10
0
% D
% Glu:
0
10
0
10
40
0
0
0
0
20
10
0
0
0
50
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
0
10
0
10
10
0
0
0
0
10
0
10
0
20
% G
% His:
0
0
0
0
0
0
0
0
10
0
0
0
0
10
0
% H
% Ile:
0
0
20
0
0
40
20
10
0
0
0
0
70
0
0
% I
% Lys:
0
0
10
0
10
10
40
0
0
0
0
0
0
60
10
% K
% Leu:
0
20
50
10
0
0
20
0
0
20
10
10
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
60
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
10
0
10
0
10
0
0
0
% N
% Pro:
60
0
0
10
0
0
0
20
0
0
0
0
0
0
0
% P
% Gln:
30
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% Q
% Arg:
0
0
10
0
0
0
10
0
0
0
0
0
0
10
0
% R
% Ser:
0
0
0
10
10
0
0
30
0
0
0
10
0
0
0
% S
% Thr:
0
0
0
10
10
0
0
10
0
0
50
10
0
0
0
% T
% Val:
0
50
0
0
0
30
0
0
20
0
0
0
10
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _