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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PROM1
All Species:
9.09
Human Site:
S578
Identified Species:
22.22
UniProt:
O43490
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43490
NP_006008.1
865
97202
S578
G
T
L
H
L
Q
N
S
F
N
I
S
E
H
L
Chimpanzee
Pan troglodytes
XP_517115
865
97216
S578
G
T
L
H
L
Q
N
S
F
N
I
S
E
R
L
Rhesus Macaque
Macaca mulatta
NP_001070888
841
94490
G571
K
K
N
R
G
T
Y
G
T
L
H
L
E
N
S
Dog
Lupus familis
XP_850831
831
93500
C563
F
E
Q
V
Y
S
D
C
K
E
N
K
G
I
Y
Cat
Felis silvestris
Mouse
Mus musculus
O54990
867
97095
V579
A
A
F
Q
L
E
N
V
V
N
V
S
D
H
F
Rat
Rattus norvegicus
Q8CJ52
834
92822
S565
K
V
L
Q
L
N
D
S
Y
D
L
D
K
H
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515242
740
82713
S472
D
L
T
V
Q
F
E
S
I
K
I
N
L
S
N
Chicken
Gallus gallus
XP_001232165
871
96765
L582
T
S
L
H
L
E
H
L
F
N
I
N
E
F
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q9W735
826
91929
Y556
D
L
T
A
Y
S
L
Y
S
N
C
K
D
N
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_798860
858
93747
L587
T
A
F
L
L
E
N
L
F
N
I
T
E
F
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
93.1
63.5
N.A.
60.6
26.5
N.A.
44.3
52.8
N.A.
41.7
N.A.
N.A.
N.A.
N.A.
26.9
Protein Similarity:
100
99.4
94.9
80.1
N.A.
78.7
48.3
N.A.
62.3
73.7
N.A.
63.3
N.A.
N.A.
N.A.
N.A.
45.7
P-Site Identity:
100
93.3
6.6
0
N.A.
33.3
33.3
N.A.
13.3
53.3
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
40
P-Site Similarity:
100
93.3
13.3
6.6
N.A.
53.3
66.6
N.A.
20
80
N.A.
20
N.A.
N.A.
N.A.
N.A.
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
20
0
10
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
10
0
0
10
0
0
0
0
% C
% Asp:
20
0
0
0
0
0
20
0
0
10
0
10
20
0
0
% D
% Glu:
0
10
0
0
0
30
10
0
0
10
0
0
50
0
0
% E
% Phe:
10
0
20
0
0
10
0
0
40
0
0
0
0
20
10
% F
% Gly:
20
0
0
0
10
0
0
10
0
0
0
0
10
0
0
% G
% His:
0
0
0
30
0
0
10
0
0
0
10
0
0
30
0
% H
% Ile:
0
0
0
0
0
0
0
0
10
0
50
0
0
10
0
% I
% Lys:
20
10
0
0
0
0
0
0
10
10
0
20
10
0
0
% K
% Leu:
0
20
40
10
60
0
10
20
0
10
10
10
10
0
40
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
10
0
0
10
40
0
0
60
10
20
0
20
10
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
10
20
10
20
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
10
0
0
0
0
0
0
0
0
0
10
10
% R
% Ser:
0
10
0
0
0
20
0
40
10
0
0
30
0
10
10
% S
% Thr:
20
20
20
0
0
10
0
0
10
0
0
10
0
0
10
% T
% Val:
0
10
0
20
0
0
0
10
10
0
10
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
20
0
10
10
10
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _