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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PROM1
All Species:
7.88
Human Site:
Y631
Identified Species:
19.26
UniProt:
O43490
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43490
NP_006008.1
865
97202
Y631
C
G
I
D
R
M
N
Y
D
S
Y
L
A
Q
T
Chimpanzee
Pan troglodytes
XP_517115
865
97216
Y631
C
G
I
D
R
M
N
Y
D
S
Y
L
A
Q
T
Rhesus Macaque
Macaca mulatta
NP_001070888
841
94490
L609
K
V
N
L
N
I
F
L
L
G
A
A
G
R
K
Dog
Lupus familis
XP_850831
831
93500
N600
N
L
S
N
D
F
K
N
M
N
V
N
I
D
N
Cat
Felis silvestris
Mouse
Mus musculus
O54990
867
97095
Y633
S
G
I
D
T
I
D
Y
S
T
Y
L
K
E
T
Rat
Rattus norvegicus
Q8CJ52
834
92822
R603
D
L
L
N
P
A
A
R
Q
N
L
E
A
L
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515242
740
82713
A509
I
D
F
A
A
Y
L
A
E
V
N
K
S
I
T
Chicken
Gallus gallus
XP_001232165
871
96765
F636
S
G
I
E
G
I
N
F
G
A
Y
L
T
E
I
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q9W735
826
91929
F594
S
K
D
V
S
R
K
F
E
G
L
K
V
D
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_798860
858
93747
R625
E
I
L
T
D
D
T
R
Q
T
L
I
D
F
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
93.1
63.5
N.A.
60.6
26.5
N.A.
44.3
52.8
N.A.
41.7
N.A.
N.A.
N.A.
N.A.
26.9
Protein Similarity:
100
99.4
94.9
80.1
N.A.
78.7
48.3
N.A.
62.3
73.7
N.A.
63.3
N.A.
N.A.
N.A.
N.A.
45.7
P-Site Identity:
100
100
0
0
N.A.
46.6
6.6
N.A.
6.6
33.3
N.A.
0
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
13.3
13.3
N.A.
73.3
26.6
N.A.
20
66.6
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
10
10
10
10
0
10
10
10
30
0
0
% A
% Cys:
20
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
10
10
30
20
10
10
0
20
0
0
0
10
20
0
% D
% Glu:
10
0
0
10
0
0
0
0
20
0
0
10
0
20
0
% E
% Phe:
0
0
10
0
0
10
10
20
0
0
0
0
0
10
0
% F
% Gly:
0
40
0
0
10
0
0
0
10
20
0
0
10
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
10
40
0
0
30
0
0
0
0
0
10
10
10
10
% I
% Lys:
10
10
0
0
0
0
20
0
0
0
0
20
10
0
10
% K
% Leu:
0
20
20
10
0
0
10
10
10
0
30
40
0
10
10
% L
% Met:
0
0
0
0
0
20
0
0
10
0
0
0
0
0
0
% M
% Asn:
10
0
10
20
10
0
30
10
0
20
10
10
0
0
10
% N
% Pro:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
20
0
0
0
0
20
10
% Q
% Arg:
0
0
0
0
20
10
0
20
0
0
0
0
0
10
10
% R
% Ser:
30
0
10
0
10
0
0
0
10
20
0
0
10
0
0
% S
% Thr:
0
0
0
10
10
0
10
0
0
20
0
0
10
0
40
% T
% Val:
0
10
0
10
0
0
0
0
0
10
10
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
10
0
30
0
0
40
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _