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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PROM1 All Species: 4.85
Human Site: Y84 Identified Species: 11.85
UniProt: O43490 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.22
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43490 NP_006008.1 865 97202 Y84 R K F L Q K A Y E S K I D Y D
Chimpanzee Pan troglodytes XP_517115 865 97216 Y84 R K V I Q K A Y E S K I D Y D
Rhesus Macaque Macaca mulatta NP_001070888 841 94490 R84 R K V I Q K A R E S K I D Y D
Dog Lupus familis XP_850831 831 93500 F84 R K I L Q K K F D F S T D Y D
Cat Felis silvestris
Mouse Mus musculus O54990 867 97095 K84 K K L I Q N K K F D I S V D S
Rat Rattus norvegicus Q8CJ52 834 92822 A81 V Q L N P F P A E L I K T L L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515242 740 82713 A20 E C D T S H R A P G A R L L L
Chicken Gallus gallus XP_001232165 871 96765 F84 R K L A Q Q K F G N T Q G D Y
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q9W735 826 91929 F88 I S A A K D K F G A I Q S E Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_798860 858 93747 S93 N T V V A D F S S V D L S L L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 93.1 63.5 N.A. 60.6 26.5 N.A. 44.3 52.8 N.A. 41.7 N.A. N.A. N.A. N.A. 26.9
Protein Similarity: 100 99.4 94.9 80.1 N.A. 78.7 48.3 N.A. 62.3 73.7 N.A. 63.3 N.A. N.A. N.A. N.A. 45.7
P-Site Identity: 100 86.6 80 53.3 N.A. 13.3 6.6 N.A. 0 20 N.A. 0 N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 93.3 86.6 66.6 N.A. 26.6 13.3 N.A. 0 40 N.A. 20 N.A. N.A. N.A. N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 20 10 0 30 20 0 10 10 0 0 0 0 % A
% Cys: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 10 0 0 20 0 0 10 10 10 0 40 20 40 % D
% Glu: 10 0 0 0 0 0 0 0 40 0 0 0 0 10 0 % E
% Phe: 0 0 10 0 0 10 10 30 10 10 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 20 10 0 0 10 0 0 % G
% His: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % H
% Ile: 10 0 10 30 0 0 0 0 0 0 30 30 0 0 0 % I
% Lys: 10 60 0 0 10 40 40 10 0 0 30 10 0 0 0 % K
% Leu: 0 0 30 20 0 0 0 0 0 10 0 10 10 30 30 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 10 0 0 10 0 10 0 0 0 10 0 0 0 0 0 % N
% Pro: 0 0 0 0 10 0 10 0 10 0 0 0 0 0 0 % P
% Gln: 0 10 0 0 60 10 0 0 0 0 0 20 0 0 0 % Q
% Arg: 50 0 0 0 0 0 10 10 0 0 0 10 0 0 0 % R
% Ser: 0 10 0 0 10 0 0 10 10 30 10 10 20 0 10 % S
% Thr: 0 10 0 10 0 0 0 0 0 0 10 10 10 0 0 % T
% Val: 10 0 30 10 0 0 0 0 0 10 0 0 10 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 20 0 0 0 0 0 40 20 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _