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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EPB41L2
All Species:
12.42
Human Site:
S748
Identified Species:
30.37
UniProt:
O43491
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43491
NP_001422.1
1005
112588
S748
S
S
S
S
S
S
E
S
E
E
E
D
V
G
E
Chimpanzee
Pan troglodytes
XP_518738
1057
118386
S800
S
S
S
S
S
S
E
S
E
E
E
D
V
G
E
Rhesus Macaque
Macaca mulatta
XP_001104857
1245
138660
S988
S
S
S
S
S
S
E
S
E
E
E
D
V
G
E
Dog
Lupus familis
XP_851612
993
109230
E735
S
S
G
G
S
E
S
E
E
E
D
V
G
E
Y
Cat
Felis silvestris
Mouse
Mus musculus
O70318
988
109815
S731
S
S
S
S
S
S
E
S
E
E
D
V
G
E
Y
Rat
Rattus norvegicus
Q9WTP0
879
98224
V656
D
S
E
T
E
G
L
V
F
A
R
D
L
K
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505707
703
78909
E480
E
E
D
F
K
E
K
E
D
Q
T
A
K
V
V
Chicken
Gallus gallus
XP_001232113
843
95195
R620
E
E
E
E
D
V
K
R
K
E
H
E
E
K
I
Frog
Xenopus laevis
P11434
801
89411
G578
T
E
E
K
P
K
E
G
M
P
N
Q
R
E
S
Zebra Danio
Brachydanio rerio
O57457
619
70690
E396
K
S
P
R
V
K
A
E
S
A
S
V
Q
Q
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.9
78.5
81.9
N.A.
82.8
42.7
N.A.
58.3
65.2
43.3
21.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
94.9
79.1
87.5
N.A.
88.9
57.2
N.A.
63
72.7
57.8
36.4
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
33.3
N.A.
66.6
13.3
N.A.
0
6.6
6.6
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
40
N.A.
73.3
26.6
N.A.
20
26.6
13.3
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
10
0
0
20
0
10
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
10
0
10
0
0
0
10
0
20
40
0
0
0
% D
% Glu:
20
30
30
10
10
20
50
30
50
60
30
10
10
30
40
% E
% Phe:
0
0
0
10
0
0
0
0
10
0
0
0
0
0
0
% F
% Gly:
0
0
10
10
0
10
0
10
0
0
0
0
20
30
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% I
% Lys:
10
0
0
10
10
20
20
0
10
0
0
0
10
20
0
% K
% Leu:
0
0
0
0
0
0
10
0
0
0
0
0
10
0
0
% L
% Met:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% N
% Pro:
0
0
10
0
10
0
0
0
0
10
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
10
0
10
10
10
0
% Q
% Arg:
0
0
0
10
0
0
0
10
0
0
10
0
10
0
0
% R
% Ser:
50
70
40
40
50
40
10
40
10
0
10
0
0
0
10
% S
% Thr:
10
0
0
10
0
0
0
0
0
0
10
0
0
0
0
% T
% Val:
0
0
0
0
10
10
0
10
0
0
0
30
30
10
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
20
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _