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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RAD51C All Species: 5.15
Human Site: S81 Identified Species: 8.72
UniProt: O43502 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.23
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43502 NP_002867.1 376 42190 S81 R Y A G T S E S H K K C T A L
Chimpanzee Pan troglodytes XP_511913 461 50997 S126 R Y A G T S E S R K K C T A L
Rhesus Macaque Macaca mulatta XP_001104781 259 29178
Dog Lupus familis XP_537695 327 36458 R65 E C L T N K P R Y A A T A E S
Cat Felis silvestris
Mouse Mus musculus O35719 350 38134 A81 R S A H L S P A F L S T T L C
Rat Rattus norvegicus NP_001123249 366 40664 E85 A L E L L E Q E H T Q G F I I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509367 364 40160 E85 A L E L L E Q E H T Q G F I I
Chicken Gallus gallus P37383 339 36885 E77 K A D K I L A E A A K L V P M
Frog Xenopus laevis Q91918 336 36642 E74 K A E K I L A E A A K L V P M
Zebra Danio Brachydanio rerio NP_001006101 362 39634 S85 H Q E Q T L G S I V T F C S G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_788113 425 46835 G104 S T S G G G D G K R T A T A F
Poplar Tree Populus trichocarpa XP_002320055 283 31959 L21 L L H E E R S L M T R L T T S
Maize Zea mays NP_001150457 294 32656 Q32 M F S D E L S Q K H I T T G S
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8GXF0 363 40196 I86 C N G S R S L I N G A K N A W
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 80.6 68 78.1 N.A. 23.9 84.5 N.A. 74.7 22 22 57.1 N.A. N.A. N.A. N.A. 43.2
Protein Similarity: 100 81.1 68.6 81.1 N.A. 39.6 90.6 N.A. 85.1 38 38.5 73.4 N.A. N.A. N.A. N.A. 58.1
P-Site Identity: 100 93.3 0 0 N.A. 26.6 6.6 N.A. 6.6 6.6 6.6 13.3 N.A. N.A. N.A. N.A. 20
P-Site Similarity: 100 93.3 0 6.6 N.A. 33.3 26.6 N.A. 26.6 20 20 20 N.A. N.A. N.A. N.A. 40
Percent
Protein Identity: 31.9 36.7 N.A. 39.1 N.A. N.A.
Protein Similarity: 51 51.6 N.A. 57.7 N.A. N.A.
P-Site Identity: 6.6 6.6 N.A. 13.3 N.A. N.A.
P-Site Similarity: 13.3 20 N.A. 20 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 15 15 22 0 0 0 15 8 15 22 15 8 8 29 0 % A
% Cys: 8 8 0 0 0 0 0 0 0 0 0 15 8 0 8 % C
% Asp: 0 0 8 8 0 0 8 0 0 0 0 0 0 0 0 % D
% Glu: 8 0 29 8 15 15 15 29 0 0 0 0 0 8 0 % E
% Phe: 0 8 0 0 0 0 0 0 8 0 0 8 15 0 8 % F
% Gly: 0 0 8 22 8 8 8 8 0 8 0 15 0 8 8 % G
% His: 8 0 8 8 0 0 0 0 22 8 0 0 0 0 0 % H
% Ile: 0 0 0 0 15 0 0 8 8 0 8 0 0 15 15 % I
% Lys: 15 0 0 15 0 8 0 0 15 15 29 8 0 0 0 % K
% Leu: 8 22 8 15 22 29 8 8 0 8 0 22 0 8 15 % L
% Met: 8 0 0 0 0 0 0 0 8 0 0 0 0 0 15 % M
% Asn: 0 8 0 0 8 0 0 0 8 0 0 0 8 0 0 % N
% Pro: 0 0 0 0 0 0 15 0 0 0 0 0 0 15 0 % P
% Gln: 0 8 0 8 0 0 15 8 0 0 15 0 0 0 0 % Q
% Arg: 22 0 0 0 8 8 0 8 8 8 8 0 0 0 0 % R
% Ser: 8 8 15 8 0 29 15 22 0 0 8 0 0 8 22 % S
% Thr: 0 8 0 8 22 0 0 0 0 22 15 22 43 8 0 % T
% Val: 0 0 0 0 0 0 0 0 0 8 0 0 15 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % W
% Tyr: 0 15 0 0 0 0 0 0 8 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _