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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RAD51C All Species: 17.88
Human Site: Y327 Identified Species: 30.26
UniProt: O43502 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43502 NP_002867.1 376 42190 Y327 K Q R L A T L Y K S P S Q K E
Chimpanzee Pan troglodytes XP_511913 461 50997 Y412 K Q R L A T L Y K S P S Q K E
Rhesus Macaque Macaca mulatta XP_001104781 259 29178 K211 Q R L A T L Y K S P S Q K E S
Dog Lupus familis XP_537695 327 36458 Q279 T L Y K S P S Q K E S T V L F
Cat Felis silvestris
Mouse Mus musculus O35719 350 38134 H302 A L G N T W G H C V N T R L I
Rat Rattus norvegicus NP_001123249 366 40664 Y318 K Q R F A T L Y K S P S Q K E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509367 364 40160 T316 D R K Q R L A T L C K S P S Q
Chicken Gallus gallus P37383 339 36885 I291 K K P I G G N I I A H A S T T
Frog Xenopus laevis Q91918 336 36642 I288 K K P I G G N I I A H A S T T
Zebra Danio Brachydanio rerio NP_001006101 362 39634 Y310 Q R R L A S L Y K S P S Q M E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_788113 425 46835 Y343 A Q R Y A N L Y K S P S K Q E
Poplar Tree Populus trichocarpa XP_002320055 283 31959 N235 R W S R C C T N R I I L Y W N
Maize Zea mays NP_001150457 294 32656 R246 W S H S C T N R L I L H W N G
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8GXF0 363 40196 N315 S W S H S C T N R V I L Y W N
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 80.6 68 78.1 N.A. 23.9 84.5 N.A. 74.7 22 22 57.1 N.A. N.A. N.A. N.A. 43.2
Protein Similarity: 100 81.1 68.6 81.1 N.A. 39.6 90.6 N.A. 85.1 38 38.5 73.4 N.A. N.A. N.A. N.A. 58.1
P-Site Identity: 100 100 0 6.6 N.A. 0 93.3 N.A. 6.6 6.6 6.6 73.3 N.A. N.A. N.A. N.A. 66.6
P-Site Similarity: 100 100 26.6 20 N.A. 20 93.3 N.A. 26.6 33.3 33.3 93.3 N.A. N.A. N.A. N.A. 80
Percent
Protein Identity: 31.9 36.7 N.A. 39.1 N.A. N.A.
Protein Similarity: 51 51.6 N.A. 57.7 N.A. N.A.
P-Site Identity: 0 6.6 N.A. 0 N.A. N.A.
P-Site Similarity: 13.3 6.6 N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 15 0 0 8 36 0 8 0 0 15 0 15 0 0 0 % A
% Cys: 0 0 0 0 15 15 0 0 8 8 0 0 0 0 0 % C
% Asp: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 8 0 0 0 8 36 % E
% Phe: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 8 % F
% Gly: 0 0 8 0 15 15 8 0 0 0 0 0 0 0 8 % G
% His: 0 0 8 8 0 0 0 8 0 0 15 8 0 0 0 % H
% Ile: 0 0 0 15 0 0 0 15 15 15 15 0 0 0 8 % I
% Lys: 36 15 8 8 0 0 0 8 43 0 8 0 15 22 0 % K
% Leu: 0 15 8 22 0 15 36 0 15 0 8 15 0 15 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % M
% Asn: 0 0 0 8 0 8 22 15 0 0 8 0 0 8 15 % N
% Pro: 0 0 15 0 0 8 0 0 0 8 36 0 8 0 0 % P
% Gln: 15 29 0 8 0 0 0 8 0 0 0 8 29 8 8 % Q
% Arg: 8 22 36 8 8 0 0 8 15 0 0 0 8 0 0 % R
% Ser: 8 8 15 8 15 8 8 0 8 36 15 43 15 8 8 % S
% Thr: 8 0 0 0 15 29 15 8 0 0 0 15 0 15 15 % T
% Val: 0 0 0 0 0 0 0 0 0 15 0 0 8 0 0 % V
% Trp: 8 15 0 0 0 8 0 0 0 0 0 0 8 15 0 % W
% Tyr: 0 0 8 8 0 0 8 36 0 0 0 0 15 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _