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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADAM20
All Species:
11.52
Human Site:
T193
Identified Species:
50.67
UniProt:
O43506
Number Species:
5
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43506
NP_003805.3
726
81603
T193
L
Q
L
S
Y
N
F
T
L
K
Q
S
S
F
V
Chimpanzee
Pan troglodytes
XP_522893
776
87080
T243
L
Q
L
S
Y
N
F
T
L
K
Q
S
S
F
V
Rhesus Macaque
Macaca mulatta
XP_001105948
722
80721
S193
G
F
E
E
A
E
N
S
A
L
E
P
K
S
A
Dog
Lupus familis
XP_537500
1476
165197
T229
L
R
A
S
Y
N
S
T
L
M
Q
N
S
Y
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9JI76
729
80831
S198
G
V
E
E
A
K
K
S
A
M
K
Q
N
Y
G
Rat
Rattus norvegicus
P70505
789
86122
T224
Q
R
Q
G
S
S
K
T
D
E
L
L
A
L
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.6
61.1
35.3
N.A.
51
33.7
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
93.4
74.7
41.5
N.A.
67.7
50.5
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
0
53.3
N.A.
0
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
13.3
80
N.A.
26.6
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
17
0
34
0
0
0
34
0
0
0
17
0
17
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
17
0
0
0
0
0
0
% D
% Glu:
0
0
34
34
0
17
0
0
0
17
17
0
0
0
0
% E
% Phe:
0
17
0
0
0
0
34
0
0
0
0
0
0
34
0
% F
% Gly:
34
0
0
17
0
0
0
0
0
0
0
0
0
0
17
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
17
34
0
0
34
17
0
17
0
0
% K
% Leu:
50
0
34
0
0
0
0
0
50
17
17
17
0
17
17
% L
% Met:
0
0
0
0
0
0
0
0
0
34
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
50
17
0
0
0
0
17
17
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
17
0
0
0
% P
% Gln:
17
34
17
0
0
0
0
0
0
0
50
17
0
0
0
% Q
% Arg:
0
34
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
50
17
17
17
34
0
0
0
34
50
17
17
% S
% Thr:
0
0
0
0
0
0
0
67
0
0
0
0
0
0
0
% T
% Val:
0
17
0
0
0
0
0
0
0
0
0
0
0
0
34
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
50
0
0
0
0
0
0
0
0
34
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _