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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TNFSF12
All Species:
15.76
Human Site:
S213
Identified Species:
49.52
UniProt:
O43508
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43508
NP_003800.1
249
27216
S213
Q
L
R
L
C
Q
V
S
G
L
L
A
L
R
P
Chimpanzee
Pan troglodytes
Q862Z7
244
25401
G208
W
Y
T
S
V
G
F
G
G
L
V
Q
L
R
R
Rhesus Macaque
Macaca mulatta
Q5TM22
244
25240
G208
W
Y
T
S
V
G
F
G
G
L
V
Q
L
R
R
Dog
Lupus familis
XP_859572
249
26994
S213
Q
L
R
L
C
Q
V
S
G
L
L
P
L
R
P
Cat
Felis silvestris
Mouse
Mus musculus
O54907
249
27422
S213
Q
L
R
L
C
Q
V
S
G
L
L
P
L
R
P
Rat
Rattus norvegicus
NP_001001513
249
27363
S213
Q
L
R
L
C
Q
V
S
G
L
L
P
L
R
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q9I8D8
272
30814
G237
E
L
Q
S
I
R
E
G
G
V
F
E
L
R
Q
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001070075
236
27131
S201
F
L
K
P
C
Q
V
S
G
L
L
R
L
N
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
22.8
23.2
89.9
N.A.
89.1
87.5
N.A.
N.A.
20.9
N.A.
32.9
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
35.3
35.7
93.1
N.A.
92.7
91.5
N.A.
N.A.
36.7
N.A.
51.8
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
26.6
26.6
93.3
N.A.
93.3
93.3
N.A.
N.A.
26.6
N.A.
60
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
33.3
33.3
93.3
N.A.
93.3
93.3
N.A.
N.A.
53.3
N.A.
66.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
13
0
0
0
% A
% Cys:
0
0
0
0
63
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
13
0
0
0
0
0
13
0
0
0
0
13
0
0
0
% E
% Phe:
13
0
0
0
0
0
25
0
0
0
13
0
0
0
0
% F
% Gly:
0
0
0
0
0
25
0
38
100
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
13
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
13
0
0
0
0
0
0
0
0
0
0
0
13
% K
% Leu:
0
75
0
50
0
0
0
0
0
88
63
0
100
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
13
0
% N
% Pro:
0
0
0
13
0
0
0
0
0
0
0
38
0
0
50
% P
% Gln:
50
0
13
0
0
63
0
0
0
0
0
25
0
0
13
% Q
% Arg:
0
0
50
0
0
13
0
0
0
0
0
13
0
88
25
% R
% Ser:
0
0
0
38
0
0
0
63
0
0
0
0
0
0
0
% S
% Thr:
0
0
25
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
25
0
63
0
0
13
25
0
0
0
0
% V
% Trp:
25
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
25
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _