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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TNFSF12
All Species:
13.64
Human Site:
S6
Identified Species:
42.86
UniProt:
O43508
Number Species:
7
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43508
NP_003800.1
249
27216
S6
_
_
M
A
A
R
R
S
Q
R
R
R
G
R
R
Chimpanzee
Pan troglodytes
Q862Z7
244
25401
L6
_
_
M
G
A
L
G
L
E
G
R
G
G
R
L
Rhesus Macaque
Macaca mulatta
Q5TM22
244
25240
L6
_
_
M
G
A
L
G
L
E
G
R
G
G
R
L
Dog
Lupus familis
XP_859572
249
26994
S6
_
_
M
A
A
R
R
S
Q
R
R
R
G
R
R
Cat
Felis silvestris
Mouse
Mus musculus
O54907
249
27422
S6
_
_
M
A
A
R
R
S
Q
R
R
R
G
R
R
Rat
Rattus norvegicus
NP_001001513
249
27363
S6
_
_
M
A
A
R
R
S
Q
R
R
R
G
R
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q9I8D8
272
30814
A8
M
N
E
A
Y
S
P
A
A
P
R
P
M
G
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001070075
236
27131
R7
_
M
Q
R
I
F
Q
R
R
R
I
R
T
L
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
22.8
23.2
89.9
N.A.
89.1
87.5
N.A.
N.A.
20.9
N.A.
32.9
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
35.3
35.7
93.1
N.A.
92.7
91.5
N.A.
N.A.
36.7
N.A.
51.8
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
38.4
38.4
100
N.A.
100
100
N.A.
N.A.
13.3
N.A.
21.4
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
46.1
46.1
100
N.A.
100
100
N.A.
N.A.
20
N.A.
35.7
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
63
75
0
0
13
13
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
13
0
0
0
0
0
25
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
13
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
25
0
0
25
0
0
25
0
25
75
13
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
13
0
0
0
0
0
13
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
25
0
25
0
0
0
0
0
13
25
% L
% Met:
13
13
75
0
0
0
0
0
0
0
0
0
13
0
0
% M
% Asn:
0
13
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
13
0
0
13
0
13
0
0
0
% P
% Gln:
0
0
13
0
0
0
13
0
50
0
0
0
0
0
0
% Q
% Arg:
0
0
0
13
0
50
50
13
13
63
88
63
0
75
63
% R
% Ser:
0
0
0
0
0
13
0
50
0
0
0
0
0
0
13
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
13
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
13
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
88
75
0
0
0
0
0
0
0
0
0
0
0
0
0
% _