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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MED7
All Species:
23.33
Human Site:
T186
Identified Species:
46.67
UniProt:
O43513
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43513
NP_001094286.1
233
27245
T186
E
A
G
M
R
V
K
T
E
P
M
D
A
D
D
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001104930
232
27090
T186
E
A
G
M
R
V
K
T
E
P
M
D
A
D
D
Dog
Lupus familis
XP_536456
469
53043
T186
E
A
G
M
R
V
K
T
E
P
M
D
A
D
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9CZB6
233
27187
A186
E
A
G
M
R
V
K
A
E
P
M
D
T
D
D
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511152
233
27138
T186
E
G
G
L
K
L
K
T
E
A
M
D
A
D
D
Chicken
Gallus gallus
Frog
Xenopus laevis
Q3B8I4
228
26281
T186
D
G
T
V
S
V
K
T
E
P
M
D
V
Q
E
Zebra Danio
Brachydanio rerio
Q7ZV35
241
27500
T197
A
G
S
S
R
L
K
T
E
P
M
D
V
D
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9GYV9
220
25689
V191
G
A
K
I
K
T
E
V
D
P
L
E
A
N
A
Honey Bee
Apis mellifera
XP_396630
227
26319
T187
D
S
K
L
A
I
N
T
D
A
M
E
S
V
D
Nematode Worm
Caenorhab. elegans
Q95Q17
251
28869
V194
R
V
K
L
Q
D
G
V
L
H
M
L
Q
E
T
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_001078525
168
19280
Q139
I
M
E
L
Q
I
Q
Q
R
K
Q
A
V
E
D
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7S2D4
347
37098
T308
P
V
P
V
G
A
R
T
G
T
T
V
G
D
R
Conservation
Percent
Protein Identity:
100
N.A.
99.5
47.9
N.A.
97
N.A.
N.A.
94.4
N.A.
78.5
76.7
N.A.
50.2
53.6
30.2
N.A.
Protein Similarity:
100
N.A.
99.5
49.2
N.A.
98.2
N.A.
N.A.
98.2
N.A.
87.1
85.4
N.A.
69
72.9
55.3
N.A.
P-Site Identity:
100
N.A.
100
100
N.A.
86.6
N.A.
N.A.
66.6
N.A.
46.6
60
N.A.
20
20
6.6
N.A.
P-Site Similarity:
100
N.A.
100
100
N.A.
86.6
N.A.
N.A.
86.6
N.A.
66.6
66.6
N.A.
66.6
66.6
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
27
N.A.
21.9
Protein Similarity:
N.A.
N.A.
N.A.
45.9
N.A.
36
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
40
N.A.
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
42
0
0
9
9
0
9
0
17
0
9
42
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
17
0
0
0
0
9
0
0
17
0
0
59
0
59
67
% D
% Glu:
42
0
9
0
0
0
9
0
59
0
0
17
0
17
9
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
9
25
42
0
9
0
9
0
9
0
0
0
9
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% H
% Ile:
9
0
0
9
0
17
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
25
0
17
0
59
0
0
9
0
0
0
0
0
% K
% Leu:
0
0
0
34
0
17
0
0
9
0
9
9
0
0
0
% L
% Met:
0
9
0
34
0
0
0
0
0
0
75
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
9
0
0
0
0
0
0
9
0
% N
% Pro:
9
0
9
0
0
0
0
0
0
59
0
0
0
0
0
% P
% Gln:
0
0
0
0
17
0
9
9
0
0
9
0
9
9
0
% Q
% Arg:
9
0
0
0
42
0
9
0
9
0
0
0
0
0
9
% R
% Ser:
0
9
9
9
9
0
0
0
0
0
0
0
9
0
0
% S
% Thr:
0
0
9
0
0
9
0
67
0
9
9
0
9
0
9
% T
% Val:
0
17
0
17
0
42
0
17
0
0
0
9
25
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _