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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATP8B1
All Species:
29.7
Human Site:
T278
Identified Species:
65.33
UniProt:
O43520
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43520
NP_005594.1
1251
143695
T278
R
L
D
K
F
T
G
T
L
F
W
R
N
T
S
Chimpanzee
Pan troglodytes
XP_512150
1250
143345
T277
R
L
D
K
F
T
G
T
L
F
W
R
N
T
S
Rhesus Macaque
Macaca mulatta
XP_001114383
1223
138692
T247
K
L
D
K
F
S
G
T
L
Y
W
K
E
N
K
Dog
Lupus familis
XP_533394
1267
145696
T295
R
L
D
K
F
T
G
T
L
F
W
R
N
T
S
Cat
Felis silvestris
Mouse
Mus musculus
Q148W0
1251
143779
T278
R
L
D
K
F
T
G
T
L
F
W
K
N
Q
S
Rat
Rattus norvegicus
NP_001099610
1259
144757
T278
R
L
D
K
F
T
G
T
L
F
W
R
N
Q
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510687
1258
144573
T278
R
L
D
K
F
T
G
T
L
T
W
R
G
E
R
Chicken
Gallus gallus
XP_429208
1172
133646
K233
K
Y
A
L
D
N
E
K
M
L
L
R
G
C
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001920510
1259
144850
T272
R
L
D
K
F
V
G
T
M
I
W
E
S
Q
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LK90
1189
135291
K243
G
T
L
Y
F
E
G
K
Q
Y
P
L
S
P
Q
Baker's Yeast
Sacchar. cerevisiae
P39524
1355
153826
T385
S
L
Y
T
Y
E
G
T
M
T
L
N
D
R
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.1
52
92.8
N.A.
94.4
93
N.A.
85
52.8
N.A.
67.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
98.6
69
96.3
N.A.
97.7
96.5
N.A.
92
67.3
N.A.
81.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
53.3
100
N.A.
86.6
93.3
N.A.
73.3
6.6
N.A.
60
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
80
100
N.A.
93.3
93.3
N.A.
73.3
26.6
N.A.
73.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
38.1
35.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
57.8
52.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% C
% Asp:
0
0
73
0
10
0
0
0
0
0
0
0
10
0
0
% D
% Glu:
0
0
0
0
0
19
10
0
0
0
0
10
10
10
0
% E
% Phe:
0
0
0
0
82
0
0
0
0
46
0
0
0
0
0
% F
% Gly:
10
0
0
0
0
0
91
0
0
0
0
0
19
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% I
% Lys:
19
0
0
73
0
0
0
19
0
0
0
19
0
0
10
% K
% Leu:
0
82
10
10
0
0
0
0
64
10
19
10
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
28
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
10
0
0
0
0
0
10
46
10
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
10
0
0
10
0
% P
% Gln:
0
0
0
0
0
0
0
0
10
0
0
0
0
28
19
% Q
% Arg:
64
0
0
0
0
0
0
0
0
0
0
55
0
10
10
% R
% Ser:
10
0
0
0
0
10
0
0
0
0
0
0
19
0
55
% S
% Thr:
0
10
0
10
0
55
0
82
0
19
0
0
0
28
10
% T
% Val:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
73
0
0
0
0
% W
% Tyr:
0
10
10
10
10
0
0
0
0
19
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _