KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATP8B1
All Species:
17.21
Human Site:
Y1245
Identified Species:
37.86
UniProt:
O43520
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43520
NP_005594.1
1251
143695
Y1245
V
A
D
G
T
A
E
Y
R
R
T
G
D
S
_
Chimpanzee
Pan troglodytes
XP_512150
1250
143345
Y1244
V
A
D
G
T
A
E
Y
R
R
T
G
D
S
_
Rhesus Macaque
Macaca mulatta
XP_001114383
1223
138692
W1198
T
T
R
S
S
S
S
W
I
E
S
L
R
R
K
Dog
Lupus familis
XP_533394
1267
145696
Y1261
I
A
D
G
T
A
E
Y
R
R
T
V
E
S
_
Cat
Felis silvestris
Mouse
Mus musculus
Q148W0
1251
143779
Y1245
I
A
D
G
T
A
E
Y
R
R
T
V
E
S
_
Rat
Rattus norvegicus
NP_001099610
1259
144757
Y1253
I
A
D
G
T
A
E
Y
R
R
T
V
E
S
_
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510687
1258
144573
E1247
L
G
E
A
A
Q
F
E
G
P
A
L
F
R
K
Chicken
Gallus gallus
XP_429208
1172
133646
K1166
T
F
S
P
N
S
D
K
Y
K
H
K
G
L
_
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001920510
1259
144850
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LK90
1189
135291
L1182
L
H
H
L
R
A
N
L
S
R
R
D
S
W
N
Baker's Yeast
Sacchar. cerevisiae
P39524
1355
153826
R1348
S
N
R
F
S
S
S
R
D
D
I
S
F
D
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.1
52
92.8
N.A.
94.4
93
N.A.
85
52.8
N.A.
67.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
98.6
69
96.3
N.A.
97.7
96.5
N.A.
92
67.3
N.A.
81.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
0
78.5
N.A.
78.5
78.5
N.A.
0
0
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
26.6
92.8
N.A.
92.8
92.8
N.A.
13.3
21.4
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
38.1
35.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
57.8
52.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
46
0
10
10
55
0
0
0
0
10
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
46
0
0
0
10
0
10
10
0
10
19
10
0
% D
% Glu:
0
0
10
0
0
0
46
10
0
10
0
0
28
0
0
% E
% Phe:
0
10
0
10
0
0
10
0
0
0
0
0
19
0
0
% F
% Gly:
0
10
0
46
0
0
0
0
10
0
0
19
10
0
0
% G
% His:
0
10
10
0
0
0
0
0
0
0
10
0
0
0
0
% H
% Ile:
28
0
0
0
0
0
0
0
10
0
10
0
0
0
10
% I
% Lys:
0
0
0
0
0
0
0
10
0
10
0
10
0
0
19
% K
% Leu:
19
0
0
10
0
0
0
10
0
0
0
19
0
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
0
0
10
0
10
0
0
0
0
0
0
0
10
% N
% Pro:
0
0
0
10
0
0
0
0
0
10
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
19
0
10
0
0
10
46
55
10
0
10
19
0
% R
% Ser:
10
0
10
10
19
28
19
0
10
0
10
10
10
46
0
% S
% Thr:
19
10
0
0
46
0
0
0
0
0
46
0
0
0
0
% T
% Val:
19
0
0
0
0
0
0
0
0
0
0
28
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
10
0
0
0
0
0
10
0
% W
% Tyr:
0
0
0
0
0
0
0
46
10
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
55
% _