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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATP8B1
All Species:
31.21
Human Site:
Y992
Identified Species:
68.67
UniProt:
O43520
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43520
NP_005594.1
1251
143695
Y992
I
T
L
Y
N
V
L
Y
T
S
L
P
V
L
L
Chimpanzee
Pan troglodytes
XP_512150
1250
143345
Y991
I
T
L
Y
N
V
L
Y
T
S
L
P
V
L
L
Rhesus Macaque
Macaca mulatta
XP_001114383
1223
138692
Y946
I
T
L
Y
N
I
V
Y
T
S
L
P
V
L
A
Dog
Lupus familis
XP_533394
1267
145696
Y1009
I
T
L
Y
N
V
L
Y
S
S
L
P
V
L
L
Cat
Felis silvestris
Mouse
Mus musculus
Q148W0
1251
143779
Y992
I
T
L
Y
N
V
L
Y
S
S
L
P
V
L
L
Rat
Rattus norvegicus
NP_001099610
1259
144757
Y992
I
T
L
Y
N
V
L
Y
S
S
L
P
V
L
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510687
1258
144573
Y994
I
T
L
Y
N
V
L
Y
S
S
L
P
V
L
L
Chicken
Gallus gallus
XP_429208
1172
133646
Q928
L
G
M
S
L
F
D
Q
D
V
D
D
R
W
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001920510
1259
144850
Y998
I
T
L
Y
N
V
C
Y
S
S
L
P
V
L
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LK90
1189
135291
F946
W
Y
E
A
Y
A
S
F
S
G
K
P
A
Y
N
Baker's Yeast
Sacchar. cerevisiae
P39524
1355
153826
F1089
L
G
Q
K
G
Q
F
F
S
V
Y
I
F
W
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.1
52
92.8
N.A.
94.4
93
N.A.
85
52.8
N.A.
67.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
98.6
69
96.3
N.A.
97.7
96.5
N.A.
92
67.3
N.A.
81.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
80
93.3
N.A.
93.3
93.3
N.A.
93.3
0
N.A.
86.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
93.3
100
N.A.
100
100
N.A.
100
13.3
N.A.
93.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
38.1
35.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
57.8
52.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
10
0
0
0
0
0
0
10
0
10
% A
% Cys:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
10
0
10
0
10
10
0
0
0
% D
% Glu:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
10
10
19
0
0
0
0
10
0
0
% F
% Gly:
0
19
0
0
10
0
0
0
0
10
0
0
0
0
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
73
0
0
0
0
10
0
0
0
0
0
10
0
0
0
% I
% Lys:
0
0
0
10
0
0
0
0
0
0
10
0
0
0
0
% K
% Leu:
19
0
73
0
10
0
55
0
0
0
73
0
0
73
64
% L
% Met:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
73
0
0
0
0
0
0
0
0
0
10
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
82
0
0
0
% P
% Gln:
0
0
10
0
0
10
0
10
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% R
% Ser:
0
0
0
10
0
0
10
0
64
73
0
0
0
0
10
% S
% Thr:
0
73
0
0
0
0
0
0
28
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
64
10
0
0
19
0
0
73
0
0
% V
% Trp:
10
0
0
0
0
0
0
0
0
0
0
0
0
19
0
% W
% Tyr:
0
10
0
73
10
0
0
73
0
0
10
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _