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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
BCL2L11
All Species:
13.64
Human Site:
S109
Identified Species:
37.5
UniProt:
O43521
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43521
NP_006529.1
198
22171
S109
D
R
S
P
A
P
M
S
C
D
K
S
T
Q
T
Chimpanzee
Pan troglodytes
XP_001143043
135
14399
L64
H
G
S
P
Q
G
P
L
A
P
P
A
S
P
G
Rhesus Macaque
Macaca mulatta
XP_001086237
198
22118
S109
D
R
S
P
A
P
M
S
C
D
K
S
T
Q
T
Dog
Lupus familis
XP_851960
167
18323
D96
S
S
G
Y
F
S
F
D
T
D
R
S
P
A
P
Cat
Felis silvestris
Mouse
Mus musculus
O54918
196
22048
S105
D
R
S
P
A
P
M
S
C
D
K
S
T
Q
T
Rat
Rattus norvegicus
O88498
196
22037
S105
D
R
S
P
A
P
M
S
C
D
K
S
T
Q
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505548
189
21315
N116
C
P
R
R
V
F
L
N
L
Q
Q
V
E
T
P
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001089746
166
17865
G95
L
V
S
K
T
S
S
G
Y
F
T
F
E
G
S
Zebra Danio
Brachydanio rerio
NP_001129263
176
19094
V99
Q
D
G
Q
N
D
E
V
W
L
S
E
H
S
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
67.6
97.9
78.7
N.A.
87.3
85.8
N.A.
26.7
N.A.
46.9
29.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
68.1
98.9
80.3
N.A.
92.4
91.4
N.A.
41.4
N.A.
55
42.9
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
13.3
100
13.3
N.A.
100
100
N.A.
0
N.A.
6.6
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
26.6
100
20
N.A.
100
100
N.A.
20
N.A.
13.3
0
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
45
0
0
0
12
0
0
12
0
12
0
% A
% Cys:
12
0
0
0
0
0
0
0
45
0
0
0
0
0
0
% C
% Asp:
45
12
0
0
0
12
0
12
0
56
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
12
0
0
0
0
12
23
0
0
% E
% Phe:
0
0
0
0
12
12
12
0
0
12
0
12
0
0
0
% F
% Gly:
0
12
23
0
0
12
0
12
0
0
0
0
0
12
12
% G
% His:
12
0
0
0
0
0
0
0
0
0
0
0
12
0
12
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
12
0
0
0
0
0
0
45
0
0
0
0
% K
% Leu:
12
0
0
0
0
0
12
12
12
12
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
45
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
12
0
0
12
0
0
0
0
0
0
0
% N
% Pro:
0
12
0
56
0
45
12
0
0
12
12
0
12
12
23
% P
% Gln:
12
0
0
12
12
0
0
0
0
12
12
0
0
45
0
% Q
% Arg:
0
45
12
12
0
0
0
0
0
0
12
0
0
0
0
% R
% Ser:
12
12
67
0
0
23
12
45
0
0
12
56
12
12
12
% S
% Thr:
0
0
0
0
12
0
0
0
12
0
12
0
45
12
45
% T
% Val:
0
12
0
0
12
0
0
12
0
0
0
12
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
12
0
0
0
0
0
0
% W
% Tyr:
0
0
0
12
0
0
0
0
12
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _