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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KCNQ3
All Species:
20.61
Human Site:
S688
Identified Species:
56.67
UniProt:
O43525
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43525
NP_004510.1
872
96742
S688
K
T
I
I
C
N
Y
S
E
T
G
P
P
E
P
Chimpanzee
Pan troglodytes
XP_001134760
872
96660
S688
K
T
I
I
C
N
Y
S
E
T
G
P
P
E
P
Rhesus Macaque
Macaca mulatta
XP_001089122
951
105836
S767
K
T
I
I
C
N
Y
S
E
T
G
P
P
E
P
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q8K3F6
873
96778
S689
K
T
I
I
C
N
Y
S
E
T
G
P
P
D
P
Rat
Rattus norvegicus
O88944
873
96879
S689
K
T
I
I
C
N
Y
S
E
S
G
P
P
D
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508650
831
93729
S638
L
K
S
I
M
N
Y
S
G
P
C
T
H
D
T
Chicken
Gallus gallus
XP_001233489
841
93324
I659
H
I
D
K
N
G
C
I
I
K
I
I
R
S
T
Frog
Xenopus laevis
P70057
377
42627
G195
F
A
T
S
A
I
R
G
I
R
F
L
Q
I
L
Zebra Danio
Brachydanio rerio
XP_697081
974
106699
S653
S
K
D
L
S
C
A
S
Q
V
S
Q
S
I
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
90.1
N.A.
N.A.
95.4
95.1
N.A.
76.9
49.6
22.3
37.9
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.7
90.6
N.A.
N.A.
97.1
97
N.A.
83.2
62.5
30.9
53.5
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
N.A.
N.A.
93.3
86.6
N.A.
26.6
0
0
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
N.A.
N.A.
100
100
N.A.
33.3
0
0
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
12
0
0
12
0
12
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
56
12
12
0
0
0
12
0
0
0
12
% C
% Asp:
0
0
23
0
0
0
0
0
0
0
0
0
0
34
0
% D
% Glu:
0
0
0
0
0
0
0
0
56
0
0
0
0
34
0
% E
% Phe:
12
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% F
% Gly:
0
0
0
0
0
12
0
12
12
0
56
0
0
0
0
% G
% His:
12
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% H
% Ile:
0
12
56
67
0
12
0
12
23
0
12
12
0
23
0
% I
% Lys:
56
23
0
12
0
0
0
0
0
12
0
0
0
0
0
% K
% Leu:
12
0
0
12
0
0
0
0
0
0
0
12
0
0
12
% L
% Met:
0
0
0
0
12
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
12
67
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
12
0
56
56
0
56
% P
% Gln:
0
0
0
0
0
0
0
0
12
0
0
12
12
0
0
% Q
% Arg:
0
0
0
0
0
0
12
0
0
12
0
0
12
0
0
% R
% Ser:
12
0
12
12
12
0
0
78
0
12
12
0
12
12
0
% S
% Thr:
0
56
12
0
0
0
0
0
0
45
0
12
0
0
23
% T
% Val:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
67
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _