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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
XRCC3
All Species:
4.55
Human Site:
S225
Identified Species:
9.09
UniProt:
O43542
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.36
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43542
NP_001093588.1
346
37850
S225
P
F
R
C
E
F
D
S
Q
A
S
A
P
R
A
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001083859
346
37901
S225
P
F
R
C
E
F
D
S
Q
A
S
A
P
R
A
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q9CXE6
349
38427
L225
P
F
R
C
E
F
H
L
Q
A
S
A
I
R
A
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508473
402
43297
A225
L
F
R
C
E
F
G
A
R
D
S
V
G
R
A
Chicken
Gallus gallus
P37383
339
36885
R235
Y
R
T
D
Y
S
G
R
G
E
L
S
A
R
Q
Frog
Xenopus laevis
Q91918
336
36642
R232
Y
R
T
D
Y
S
G
R
G
E
L
S
A
R
Q
Zebra Danio
Brachydanio rerio
NP_001013559
352
38603
A225
L
F
R
S
E
F
Q
A
D
E
A
V
Q
R
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q27297
336
36629
R232
Y
R
S
D
Y
I
G
R
G
E
L
A
A
R
Q
Honey Bee
Apis mellifera
XP_001122070
169
18928
G67
V
Q
L
P
K
T
E
G
G
L
A
A
G
A
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001204119
355
39399
L221
I
F
R
S
E
F
E
L
R
D
T
I
R
R
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q9XED7
340
36708
R236
Y
R
T
D
F
S
G
R
G
E
L
S
A
R
Q
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P25301
460
52229
N237
H
L
R
V
E
L
Q
N
K
S
F
R
E
S
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
97.1
N.A.
N.A.
73
N.A.
N.A.
53.4
26.5
24.2
52.5
N.A.
27.1
23.9
N.A.
43.6
Protein Similarity:
100
N.A.
97.9
N.A.
N.A.
83
N.A.
N.A.
69.9
44.2
41.9
68.4
N.A.
44.5
36.4
N.A.
59.1
P-Site Identity:
100
N.A.
100
N.A.
N.A.
80
N.A.
N.A.
53.3
6.6
6.6
33.3
N.A.
13.3
6.6
N.A.
40
P-Site Similarity:
100
N.A.
100
N.A.
N.A.
80
N.A.
N.A.
66.6
13.3
13.3
53.3
N.A.
13.3
26.6
N.A.
60
Percent
Protein Identity:
N.A.
27.7
N.A.
N.A.
21.7
N.A.
Protein Similarity:
N.A.
46.5
N.A.
N.A.
39.5
N.A.
P-Site Identity:
N.A.
6.6
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
13.3
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
17
0
25
17
42
34
9
42
% A
% Cys:
0
0
0
34
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
34
0
0
17
0
9
17
0
0
0
0
0
% D
% Glu:
0
0
0
0
59
0
17
0
0
42
0
0
9
0
0
% E
% Phe:
0
50
0
0
9
50
0
0
0
0
9
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
42
9
42
0
0
0
17
0
0
% G
% His:
9
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% H
% Ile:
9
0
0
0
0
9
0
0
0
0
0
9
9
0
9
% I
% Lys:
0
0
0
0
9
0
0
0
9
0
0
0
0
0
0
% K
% Leu:
17
9
9
0
0
9
0
17
0
9
34
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% N
% Pro:
25
0
0
9
0
0
0
0
0
0
0
0
17
0
0
% P
% Gln:
0
9
0
0
0
0
17
0
25
0
0
0
9
0
42
% Q
% Arg:
0
34
59
0
0
0
0
34
17
0
0
9
9
84
0
% R
% Ser:
0
0
9
17
0
25
0
17
0
9
34
25
0
9
9
% S
% Thr:
0
0
25
0
0
9
0
0
0
0
9
0
0
0
0
% T
% Val:
9
0
0
9
0
0
0
0
0
0
0
17
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
34
0
0
0
25
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _