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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
XRCC3
All Species:
12.12
Human Site:
S281
Identified Species:
24.24
UniProt:
O43542
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43542
NP_001093588.1
346
37850
S281
G
F
W
D
E
R
V
S
P
A
L
G
I
T
W
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001083859
346
37901
S281
G
F
W
D
E
R
V
S
P
A
L
G
I
T
W
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q9CXE6
349
38427
S281
G
A
S
E
E
R
L
S
P
A
L
G
I
T
W
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508473
402
43297
T281
G
L
E
E
E
A
V
T
P
A
L
G
L
T
W
Chicken
Gallus gallus
P37383
339
36885
K285
M
F
A
A
D
P
K
K
P
I
G
G
N
I
I
Frog
Xenopus laevis
Q91918
336
36642
K282
M
F
A
A
D
P
K
K
P
I
G
G
N
I
I
Zebra Danio
Brachydanio rerio
NP_001013559
352
38603
L281
G
L
V
G
S
K
V
L
P
A
L
G
I
A
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q27297
336
36629
I283
M
F
D
A
K
K
P
I
G
G
H
I
M
A
H
Honey Bee
Apis mellifera
XP_001122070
169
18928
E117
E
H
I
S
T
I
E
E
L
E
I
Y
S
I
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001204119
355
39399
M271
D
P
T
E
S
E
M
M
P
A
L
G
L
T
W
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q9XED7
340
36708
K286
M
F
A
G
P
Q
I
K
P
I
G
G
N
I
M
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P25301
460
52229
V385
K
R
K
F
D
Y
R
V
P
N
L
G
L
T
W
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
97.1
N.A.
N.A.
73
N.A.
N.A.
53.4
26.5
24.2
52.5
N.A.
27.1
23.9
N.A.
43.6
Protein Similarity:
100
N.A.
97.9
N.A.
N.A.
83
N.A.
N.A.
69.9
44.2
41.9
68.4
N.A.
44.5
36.4
N.A.
59.1
P-Site Identity:
100
N.A.
100
N.A.
N.A.
73.3
N.A.
N.A.
60
20
20
53.3
N.A.
6.6
0
N.A.
40
P-Site Similarity:
100
N.A.
100
N.A.
N.A.
86.6
N.A.
N.A.
80
26.6
26.6
60
N.A.
26.6
6.6
N.A.
60
Percent
Protein Identity:
N.A.
27.7
N.A.
N.A.
21.7
N.A.
Protein Similarity:
N.A.
46.5
N.A.
N.A.
39.5
N.A.
P-Site Identity:
N.A.
20
N.A.
N.A.
33.3
N.A.
P-Site Similarity:
N.A.
33.3
N.A.
N.A.
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
25
25
0
9
0
0
0
50
0
0
0
17
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
0
9
17
25
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
9
0
9
25
34
9
9
9
0
9
0
0
0
0
0
% E
% Phe:
0
50
0
9
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
42
0
0
17
0
0
0
0
9
9
25
84
0
0
0
% G
% His:
0
9
0
0
0
0
0
0
0
0
9
0
0
0
9
% H
% Ile:
0
0
9
0
0
9
9
9
0
25
9
9
34
34
17
% I
% Lys:
9
0
9
0
9
17
17
25
0
0
0
0
0
0
0
% K
% Leu:
0
17
0
0
0
0
9
9
9
0
59
0
25
0
0
% L
% Met:
34
0
0
0
0
0
9
9
0
0
0
0
9
0
9
% M
% Asn:
0
0
0
0
0
0
0
0
0
9
0
0
25
0
0
% N
% Pro:
0
9
0
0
9
17
9
0
84
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
9
0
0
0
25
9
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
9
9
17
0
0
25
0
0
0
0
9
0
0
% S
% Thr:
0
0
9
0
9
0
0
9
0
0
0
0
0
50
0
% T
% Val:
0
0
9
0
0
0
34
9
0
0
0
0
0
0
0
% V
% Trp:
0
0
17
0
0
0
0
0
0
0
0
0
0
0
59
% W
% Tyr:
0
0
0
0
0
9
0
0
0
0
0
9
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _