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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
XRCC3
All Species:
7.88
Human Site:
T189
Identified Species:
15.76
UniProt:
O43542
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43542
NP_001093588.1
346
37850
T189
E
H
V
A
D
V
D
T
L
L
E
C
V
N
K
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001083859
346
37901
A189
E
H
V
A
D
V
D
A
L
L
E
C
V
N
K
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q9CXE6
349
38427
T189
E
H
A
A
D
V
D
T
L
L
E
C
V
S
K
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508473
402
43297
T189
E
H
A
A
D
L
E
T
L
Q
D
C
V
G
K
Chicken
Gallus gallus
P37383
339
36885
H199
A
R
G
F
N
T
D
H
Q
T
Q
L
L
Y
Q
Frog
Xenopus laevis
Q91918
336
36642
H196
A
R
A
F
N
T
D
H
Q
T
Q
L
L
Y
Q
Zebra Danio
Brachydanio rerio
NP_001013559
352
38603
A189
E
H
A
A
D
L
E
A
L
Q
V
C
V
S
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q27297
336
36629
Q196
T
R
A
H
N
S
D
Q
Q
T
K
L
I
Q
M
Honey Bee
Apis mellifera
XP_001122070
169
18928
G31
K
F
D
T
L
L
Q
G
G
I
T
N
R
G
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001204119
355
39399
Q185
E
H
A
A
E
K
D
Q
L
W
H
C
L
E
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q9XED7
340
36708
H200
A
R
A
Y
N
T
D
H
Q
S
R
L
L
L
E
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P25301
460
52229
E201
C
N
D
L
I
N
Q
E
H
I
I
N
V
Q
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
97.1
N.A.
N.A.
73
N.A.
N.A.
53.4
26.5
24.2
52.5
N.A.
27.1
23.9
N.A.
43.6
Protein Similarity:
100
N.A.
97.9
N.A.
N.A.
83
N.A.
N.A.
69.9
44.2
41.9
68.4
N.A.
44.5
36.4
N.A.
59.1
P-Site Identity:
100
N.A.
93.3
N.A.
N.A.
86.6
N.A.
N.A.
60
6.6
6.6
46.6
N.A.
6.6
0
N.A.
46.6
P-Site Similarity:
100
N.A.
93.3
N.A.
N.A.
93.3
N.A.
N.A.
80
33.3
33.3
73.3
N.A.
26.6
20
N.A.
60
Percent
Protein Identity:
N.A.
27.7
N.A.
N.A.
21.7
N.A.
Protein Similarity:
N.A.
46.5
N.A.
N.A.
39.5
N.A.
P-Site Identity:
N.A.
6.6
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
26.6
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
25
0
59
50
0
0
0
17
0
0
0
0
0
0
0
% A
% Cys:
9
0
0
0
0
0
0
0
0
0
0
50
0
0
0
% C
% Asp:
0
0
17
0
42
0
67
0
0
0
9
0
0
0
0
% D
% Glu:
50
0
0
0
9
0
17
9
0
0
25
0
0
9
9
% E
% Phe:
0
9
0
17
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
9
0
0
0
0
9
9
0
0
0
0
17
0
% G
% His:
0
50
0
9
0
0
0
25
9
0
9
0
0
0
0
% H
% Ile:
0
0
0
0
9
0
0
0
0
17
9
0
9
0
9
% I
% Lys:
9
0
0
0
0
9
0
0
0
0
9
0
0
0
42
% K
% Leu:
0
0
0
9
9
25
0
0
50
25
0
34
34
9
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% M
% Asn:
0
9
0
0
34
9
0
0
0
0
0
17
0
17
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
17
17
34
17
17
0
0
17
25
% Q
% Arg:
0
34
0
0
0
0
0
0
0
0
9
0
9
0
0
% R
% Ser:
0
0
0
0
0
9
0
0
0
9
0
0
0
17
0
% S
% Thr:
9
0
0
9
0
25
0
25
0
25
9
0
0
0
0
% T
% Val:
0
0
17
0
0
25
0
0
0
0
9
0
50
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% W
% Tyr:
0
0
0
9
0
0
0
0
0
0
0
0
0
17
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _