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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
XRCC2
All Species:
24.24
Human Site:
S104
Identified Species:
53.33
UniProt:
O43543
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43543
NP_005422.1
280
31956
S104
E
H
R
L
S
Q
S
S
E
E
I
I
K
Y
C
Chimpanzee
Pan troglodytes
XP_001140134
280
31906
S104
E
H
R
L
S
Q
S
S
E
E
I
I
K
Y
C
Rhesus Macaque
Macaca mulatta
XP_001108141
280
32026
S104
E
H
R
L
S
Q
S
S
E
E
I
I
K
Y
C
Dog
Lupus familis
XP_532771
275
31717
E101
H
R
L
S
Q
S
S
E
E
M
V
K
H
C
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9CX47
278
31372
S104
E
H
R
L
S
Q
S
S
E
E
A
M
K
L
C
Rat
Rattus norvegicus
NP_001102685
278
31384
S104
E
H
R
L
S
Q
S
S
E
E
A
I
K
L
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513030
299
33944
M111
D
T
D
Y
H
F
D
M
L
R
L
I
T
I
L
Chicken
Gallus gallus
XP_418543
379
42525
T205
E
H
R
L
E
Q
S
T
E
E
M
M
K
R
C
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_685091
302
33584
S104
E
G
R
L
A
E
D
S
K
T
G
S
E
N
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_791162
365
40672
V177
S
P
P
S
E
E
E
V
E
T
F
L
K
A
C
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q682D3
372
42343
Y145
T
V
F
D
E
E
L
Y
A
S
C
M
K
R
F
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
96.4
79.2
N.A.
77.8
79.2
N.A.
67.8
52.7
N.A.
49.3
N.A.
N.A.
N.A.
N.A.
25.4
Protein Similarity:
100
99.6
97.8
88.2
N.A.
89.2
91.4
N.A.
76.2
62
N.A.
65.8
N.A.
N.A.
N.A.
N.A.
40.8
P-Site Identity:
100
100
100
13.3
N.A.
80
86.6
N.A.
6.6
66.6
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
20
P-Site Similarity:
100
100
100
20
N.A.
86.6
86.6
N.A.
20
86.6
N.A.
53.3
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
26.3
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
41.6
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
0
0
0
10
0
19
0
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
10
0
0
10
64
% C
% Asp:
10
0
10
10
0
0
19
0
0
0
0
0
0
0
0
% D
% Glu:
64
0
0
0
28
28
10
10
73
55
0
0
10
0
10
% E
% Phe:
0
0
10
0
0
10
0
0
0
0
10
0
0
0
10
% F
% Gly:
0
10
0
0
0
0
0
0
0
0
10
0
0
0
0
% G
% His:
10
55
0
0
10
0
0
0
0
0
0
0
10
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
28
46
0
10
0
% I
% Lys:
0
0
0
0
0
0
0
0
10
0
0
10
73
0
0
% K
% Leu:
0
0
10
64
0
0
10
0
10
0
10
10
0
19
19
% L
% Met:
0
0
0
0
0
0
0
10
0
10
10
28
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% N
% Pro:
0
10
10
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
10
55
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
10
64
0
0
0
0
0
0
10
0
0
0
19
0
% R
% Ser:
10
0
0
19
46
10
64
55
0
10
0
10
0
0
0
% S
% Thr:
10
10
0
0
0
0
0
10
0
19
0
0
10
0
0
% T
% Val:
0
10
0
0
0
0
0
10
0
0
10
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
0
0
0
10
0
0
0
0
0
28
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _