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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: XRCC2 All Species: 15.45
Human Site: S262 Identified Species: 34
UniProt: O43543 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43543 NP_005422.1 280 31956 S262 L V S R C L K S N S L K K H F
Chimpanzee Pan troglodytes XP_001140134 280 31906 S262 L V S R C L K S N S L K K H F
Rhesus Macaque Macaca mulatta XP_001108141 280 32026 S262 L V S R C L K S N S F K K H F
Dog Lupus familis XP_532771 275 31717 N258 V S R H L K S N S L K K H T F
Cat Felis silvestris
Mouse Mus musculus Q9CX47 278 31372 N261 V S R H L K S N S L K K H S F
Rat Rattus norvegicus NP_001102685 278 31384 N261 V S R H L K S N S L K K H V F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513030 299 33944 S281 F T S C H L K S N R F A K R F
Chicken Gallus gallus XP_418543 379 42525 K362 L V S C H L K K K H V A K R S
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_685091 302 33584 T281 T A C T S I L T K G V K K C S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_791162 365 40672 S348 S V L K H K A S G N M Y S C Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q682D3 372 42343 Y346 L T T I K P F Y S K L L L I Y
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.2 96.4 79.2 N.A. 77.8 79.2 N.A. 67.8 52.7 N.A. 49.3 N.A. N.A. N.A. N.A. 25.4
Protein Similarity: 100 99.6 97.8 88.2 N.A. 89.2 91.4 N.A. 76.2 62 N.A. 65.8 N.A. N.A. N.A. N.A. 40.8
P-Site Identity: 100 100 93.3 13.3 N.A. 13.3 13.3 N.A. 46.6 40 N.A. 13.3 N.A. N.A. N.A. N.A. 13.3
P-Site Similarity: 100 100 93.3 33.3 N.A. 33.3 33.3 N.A. 46.6 46.6 N.A. 33.3 N.A. N.A. N.A. N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. 26.3 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 41.6 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 33.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 0 0 0 0 10 0 0 0 0 19 0 0 0 % A
% Cys: 0 0 10 19 28 0 0 0 0 0 0 0 0 19 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 10 0 0 0 0 0 10 0 0 0 19 0 0 0 64 % F
% Gly: 0 0 0 0 0 0 0 0 10 10 0 0 0 0 0 % G
% His: 0 0 0 28 28 0 0 0 0 10 0 0 28 28 0 % H
% Ile: 0 0 0 10 0 10 0 0 0 0 0 0 0 10 0 % I
% Lys: 0 0 0 10 10 37 46 10 19 10 28 64 55 0 0 % K
% Leu: 46 0 10 0 28 46 10 0 0 28 28 10 10 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 28 37 10 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % Q
% Arg: 0 0 28 28 0 0 0 0 0 10 0 0 0 19 0 % R
% Ser: 10 28 46 0 10 0 28 46 37 28 0 0 10 10 19 % S
% Thr: 10 19 10 10 0 0 0 10 0 0 0 0 0 10 0 % T
% Val: 28 46 0 0 0 0 0 0 0 0 19 0 0 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 10 0 0 0 10 0 0 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _