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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
XRCC2
All Species:
10.91
Human Site:
Y223
Identified Species:
24
UniProt:
O43543
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.3
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43543
NP_005422.1
280
31956
Y223
L
C
D
V
D
I
D
Y
R
P
Y
L
C
K
A
Chimpanzee
Pan troglodytes
XP_001140134
280
31906
Y223
L
C
D
V
D
I
D
Y
R
P
Y
L
C
K
A
Rhesus Macaque
Macaca mulatta
XP_001108141
280
32026
Y223
L
R
D
V
D
V
D
Y
R
P
Y
L
C
K
A
Dog
Lupus familis
XP_532771
275
31717
R220
K
E
A
D
A
D
Y
R
P
Y
L
C
K
E
W
Cat
Felis silvestris
Mouse
Mus musculus
Q9CX47
278
31372
R223
C
D
G
D
M
G
Y
R
A
Y
L
C
K
A
W
Rat
Rattus norvegicus
NP_001102685
278
31384
R223
C
D
G
D
M
D
Y
R
A
Y
L
C
K
A
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513030
299
33944
N230
R
S
S
K
A
S
E
N
S
A
S
A
W
E
G
Chicken
Gallus gallus
XP_418543
379
42525
R324
S
E
I
D
A
D
Y
R
P
Y
L
C
K
S
W
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_685091
302
33584
S223
V
S
D
V
H
G
S
S
S
S
S
S
S
R
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_791162
365
40672
S296
T
D
H
S
N
R
T
S
T
T
S
V
K
L
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q682D3
372
42343
D264
N
R
K
V
S
S
N
D
H
F
S
G
N
V
A
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
96.4
79.2
N.A.
77.8
79.2
N.A.
67.8
52.7
N.A.
49.3
N.A.
N.A.
N.A.
N.A.
25.4
Protein Similarity:
100
99.6
97.8
88.2
N.A.
89.2
91.4
N.A.
76.2
62
N.A.
65.8
N.A.
N.A.
N.A.
N.A.
40.8
P-Site Identity:
100
100
86.6
0
N.A.
0
0
N.A.
0
0
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
93.3
6.6
N.A.
0
0
N.A.
13.3
0
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
26.3
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
41.6
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
28
0
0
0
19
10
0
10
0
19
37
% A
% Cys:
19
19
0
0
0
0
0
0
0
0
0
37
28
0
0
% C
% Asp:
0
28
37
37
28
28
28
10
0
0
0
0
0
0
0
% D
% Glu:
0
19
0
0
0
0
10
0
0
0
0
0
0
19
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% F
% Gly:
0
0
19
0
0
19
0
0
0
0
0
10
0
0
10
% G
% His:
0
0
10
0
10
0
0
0
10
0
0
0
0
0
0
% H
% Ile:
0
0
10
0
0
19
0
0
0
0
0
0
0
0
0
% I
% Lys:
10
0
10
10
0
0
0
0
0
0
0
0
46
28
0
% K
% Leu:
28
0
0
0
0
0
0
0
0
0
37
28
0
10
0
% L
% Met:
0
0
0
0
19
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
0
0
10
0
10
10
0
0
0
0
10
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
19
28
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
10
19
0
0
0
10
0
37
28
0
0
0
0
10
10
% R
% Ser:
10
19
10
10
10
19
10
19
19
10
37
10
10
10
10
% S
% Thr:
10
0
0
0
0
0
10
0
10
10
0
0
0
0
0
% T
% Val:
10
0
0
46
0
10
0
0
0
0
0
10
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
37
% W
% Tyr:
0
0
0
0
0
0
37
28
0
37
28
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _