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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SGCE All Species: 31.82
Human Site: T353 Identified Species: 70
UniProt: O43556 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43556 NP_001092870.1 437 49851 T353 V E K R N M Q T P D I Q L V H
Chimpanzee Pan troglodytes XP_519209 428 48732 E344 Y I M C C R R E G V I Q L V H
Rhesus Macaque Macaca mulatta XP_001096891 437 49847 T353 V E K R N M Q T P D I Q L V H
Dog Lupus familis XP_860806 408 46494 T324 V E K R N M Q T P D I Q L V H
Cat Felis silvestris
Mouse Mus musculus O70258 437 49717 T353 V E K R D M Q T P D I Q L V H
Rat Rattus norvegicus Q6YAT4 437 49822 T353 V E K R N M Q T P D I Q L V H
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512055 543 59734 T391 V E K R N M Q T P D I Q L V H
Chicken Gallus gallus XP_418667 465 51872 T381 V E K R N M Q T P D I Q L V H
Frog Xenopus laevis NP_001089343 304 34504 K221 E L R D M S K K R E I A W P L
Zebra Danio Brachydanio rerio NP_001002594 414 46580 T330 V E K R N M Q T P D I Q L V H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_794953 451 50254 R362 T P T V G S Q R S H S R S R G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.9 99.7 91.5 N.A. 94.9 95.8 N.A. 71.2 76.9 49.6 78.4 N.A. N.A. N.A. N.A. 30.6
Protein Similarity: 100 97.9 100 93.1 N.A. 97.9 98.4 N.A. 75.1 80.8 59.5 86.2 N.A. N.A. N.A. N.A. 47.4
P-Site Identity: 100 33.3 100 100 N.A. 93.3 100 N.A. 100 100 6.6 100 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 40 100 100 N.A. 100 100 N.A. 100 100 26.6 100 N.A. N.A. N.A. N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % A
% Cys: 0 0 0 10 10 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 10 10 0 0 0 0 73 0 0 0 0 0 % D
% Glu: 10 73 0 0 0 0 0 10 0 10 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 10 0 0 0 10 0 0 0 0 0 10 % G
% His: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 82 % H
% Ile: 0 10 0 0 0 0 0 0 0 0 91 0 0 0 0 % I
% Lys: 0 0 73 0 0 0 10 10 0 0 0 0 0 0 0 % K
% Leu: 0 10 0 0 0 0 0 0 0 0 0 0 82 0 10 % L
% Met: 0 0 10 0 10 73 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 64 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 10 0 0 0 0 0 0 73 0 0 0 0 10 0 % P
% Gln: 0 0 0 0 0 0 82 0 0 0 0 82 0 0 0 % Q
% Arg: 0 0 10 73 0 10 10 10 10 0 0 10 0 10 0 % R
% Ser: 0 0 0 0 0 19 0 0 10 0 10 0 10 0 0 % S
% Thr: 10 0 10 0 0 0 0 73 0 0 0 0 0 0 0 % T
% Val: 73 0 0 10 0 0 0 0 0 10 0 0 0 82 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % W
% Tyr: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _